Infections of the genitourinary tract can be caused by a number of viral, bacterial, fungal, and parasitic organisms ( Table 16.1 ). Although many of these organisms are also seen in other locations, some of them have a predilection for…
Pathogenic involvement of joints and other synovium-lined structures, including tendon sheaths and bursae, is a relatively uncommon but important form of infection. Its significance is related to the severe destruction of musculoskeletal structures it can cause, which often results in…
Osteomyelitis is defined literally as inflammation of bone and marrow, albeit, the common use of the term virtually always implies infection. Infection of the skeleton, the largest organ system of the body, is important because it is a major site…
The bone marrow and spleen may be affected by a wide variety of infectious agents. Pathologists must be aware of the clinical concern for infection to initiate appropriate studies to detect microorganisms and be prepared to recognize features of infection…
Lymph nodes play an important role in reaction to infectious processes. In many cases the histologic changes are nonspecific and a particular etiology cannot be assigned; in other cases the findings are characteristic of specific entities. This chapter focuses on…
The liver is the target of many infectious agents, most notably hepatotropic viruses such as hepatitis B virus (HBV) and hepatitis C virus (HCV). In addition, many infectious organisms can involve the liver in the setting of disseminated infection, in…
The surgical pathologist plays a key role in the diagnosis of gastrointestinal infection. Virtually all types of pathogenic microbes can cause gastrointestinal infection, so the diagnostic pathologist must be cognizant of their varied histologic manifestations and acquainted with the complex…
Introduction Infections can involve all three layers of the heart, and virtually all classes of organisms infect cardiac tissues. Because the entire cardiac output is delivered to the lungs and other vital organs by the cardiac ventricles with each cardiac…
Introduction In its role as a portal between the ambient environment and the internal milieu, the lung is also the most frequent site of serious infection. A variety of factors predispose to pulmonary infection, including distortions in lung anatomy, decreased…
The head and neck area is arguably the most complex area of the human body; with its many physical connections to the outside environment, it plays host to myriad infectious processes. The aim of this chapter is to provide the…