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Summary and Key Features Niacinamide is a water-soluble, stable, low molecular weight vitamin that readily penetrates the stratum corneum. Niacinamide has been used topically in prevention of photodamage, reduction in acne, improvement in bullous pemphigoid, and treatment of rosacea and…

Summary and Key Features L-ascorbic acid is a water soluble antioxidant Vitamin C serves as a co-factor for the enzymes that synthesize collagen Topically applied vitamin C confers photoprotection Vitamin C inhibits tyrosinase and is an effective skin lightener Topical…

Summary and Key Features Retinoids are naturally occurring derivatives of betacarotene ascribed as vitamin A and its direct metabolites. Retinol has been studied extensively for topical treatment of photodamage and acne with currently marketed cosmetic products containing relatively low levels…

Summary and Key Features Cosmeceutical formulations are tested through noninvasive techniques to insure consumer efficacy. Photography and image analysis are use to analyze surface texture and wrinkle improvement through the use of cosmeceuticals. Transepidermal water loss is a measure of…

Summary and Key Features Delivery systems are intended to maximize performance and provide consumer-perceivable benefits with excellent aesthetic attributes to provide a unique feel and form. Successful delivery systems must consider pH, solubility, compatibility, stability, and preservation. Emulsions are the…

Summary and Key Features Stratum corneum (SC) is one of the largest organs of the body, protecting us against external environmental stresses to regulating water and heat and also serving as an immunological barrier While there is a host of…

Introduction This chapter is our vision for the way forward from gaps to goals . We first summarize the major gaps that exist in order to provide optimal care for HS patients. We then outline the journey to address these…

Introduction Since early 2000, there has been a dramatic increase in the number of publications and clinical trials devoted to moderate to severe hidradenitis suppurativa (HS). HS is a complex disease process in which a complete mechanism is still unknown.…

Introduction Support groups are an invaluable tool to help individuals cope with a multitude of diseases, conditions, and phases in life. They are beneficial to patients as well as to family members and caregivers. Support groups can be in-person with…

Introduction Successful treatment of a patient with hidradenitis suppurativa (HS) requires a multidisciplinary approach. As such, establishing a multidisciplinary HS clinic is crucial to address this multifaceted disease. Having a basic treatment algorithm, expertise in the field, access to other…