Introduction Hidradenitis suppurativa (HS) is characterized by relapsing, painful, suppurating, bleeding nodules, abscesses, and sinus tracts that primarily affect intertriginous skin. Aside from its debilitating physical manifestations, the disease carries a profound psychological burden and socioeconomic impact. These factors contribute…
Introduction to Wound Care in Hidradenitis Suppurativa The most important step in managing hidradenitis suppurativa (HS)-related wounds is to treat the underlying disease with appropriate medical and surgical approaches. Even so, proper local wound care is a key cornerstone of…
Introduction Pain is the most burdensome symptom of hidradenitis suppurativa (HS), accounting for greater impairment in HS-related quality of life (QoL) than even disease severity. Although it has received relatively less attention, pruritus is also common in HS and contributes…
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory disorder with a complex, multifactorial, and incompletely elucidated pathophysiology. Among relevant host factors are a number of important inflammatory pathways, including increased production of oxygen free radicals, enhanced expression of toll-like receptors…
Introduction The pathogenesis of hidradenitis suppurativa (HS) remains to be fully elucidated. Genetic susceptibility along with hormonal fluctuations and immune dysregulation are all thought to contribute to HS development. HS tends to occur in patients with comorbid conditions associated with…
Introduction Antibiotics alone, or in combination with other therapeutic strategies, have been empirically used in hidradenitis suppurativa (HS) with variable success, resulting only in temporary symptom relief in the disease process. Although very few randomized controlled studies have been performed…
Introduction Topical therapy is a mainstay of dermatological treatment and holds many advantages, including ease of use, relative lack of systemic side effects, and patient-directed application. In hidradenitis suppurativa (HS), topical therapeutics are often used for early-stage lesions or as…
Introduction Long considered an orphan disease until recent years, hidradenitis suppurativa (HS) is rapidly gaining attention in the healthcare field with a growing spotlight on investigating HS pathogenesis, epidemiology, and treatment options. To better navigate the expanding therapeutic options available,…
Introduction Outcome measures play an important role in the field of dermatology, both in routine clinical practice and in clinical research trials. In clinical settings, robust outcome measures serve to classify disease severity, which can direct treatment choice. Outcome measures…
Introduction Hidradenitis suppurativa (HS) is an inflammatory condition characterized by painful and sometimes purulent nodules, abscesses, and sinus tracts located in intertriginous regions. Lesions may progress to form hypertrophic scars or dermal tunnels. HS patients are regarded as having one…