Introduction The psoriasiform reaction pattern is defined morphologically as the presence of epidermal hyperplasia with elongation of the rete ridges in a regular manner. This definition encompasses a heterogeneous group of dermatological conditions. This morphological concept is much broader than…
Introduction The lichenoid reaction pattern (lichenoid tissue reaction, interface dermatitis) is characterized histologically by epidermal basal cell damage. This takes the form of cell death and/or vacuolar change (liquefaction degeneration). The cell death usually involves only scattered cells in the…
In the previous chapter, an orderly approach to the diagnosis of inflammatory skin lesions was discussed. This chapter records in list form some useful points that may assist in reaching a correct diagnosis. Many of the clues that follow produce…
Introduction Dermatopathology requires years of training and practice to attain an acceptable level of diagnostic skill. Many have found this process an exciting and challenging one, well worth the expenditure of time and intellectual effort. To the trainee, there seems…
Definition Squamous cell carcinoma with a malignant spindle cell or heterologous sarcomatoid component Clinical features Usually manifests as a white-gray, mixed exophytic and endophytic mass on the glans penis You’re Reading a Preview Become a Clinical Tree membership for Full…
The purpose of this chapter is to provide selected highlights of new information (or, in some cases, revitalized old information) that has become available in the realm of dermatopathology, along with the page number where each one (and its references)…
Definition A variant of verrucous carcinoma corresponding to a low-grade verruciform squamous cell carcinoma characterized by deeply infiltrating and interconnected tumor nests forming a burrowing pattern Clinical features Epidemiology Rare, with only a few bona fide cases reported Not related…
Definition Highly aggressive squamous cell carcinoma composed of infiltrative solid tumor nests with central acantholysis as a prominent feature, simulating a glandular lumen Clinical features Epidemiology Rare, with only a few cases reported You’re Reading a Preview Become a Clinical…
Definition A well-differentiated squamous cell carcinoma (SCC) of the penis with endophytic growth that preferentially involves the foreskin and usually arises in association with lichen sclerosus Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access…
Definition A variant of squamous cell carcinoma (SCC) with verruciform growth pattern, not associated with HPV infection Clinical features Epidemiology Accounts for 5%–15% of penile SCC Affects patients in fifth and sixth decades of life Not associated with HPV infection…