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Risk In general population: 0.4–1.3 cases per 100,000; AIDS pts: 2–7 cases per 1000. Impact of cryptococcosis: Approximately 625,000 deaths each year worldwide. Underlying immunocompromised conditions and risk factors: AIDS, systemic lupus erythematous, prolonged treatment with corticosteroids, organ transplantation, advanced…

Risk Represents approximately 4.8% of cases of craniosynostosis at birth. Birth prevalence of 1.6:100,000 births. Estimated prevalence in general population of Europe is 0.9:100,000. No race predilection. Perioperative Risks Difficult BMV, difficult intubation, massive blood loss, arterial gas embolism Worry…

Risk Children between 6 mo-6 y are at risk (6 mo–3 y at greatest risk). Children with underlying airway abnormalities (e.g., subglottic stenosis) or difficult intubations (e.g., micrognathia) and symptoms are at increased risk and require particular planning. Perioperative Risks…

Risk Incidence of 3.1–14.6 cases per 100,000 person-years; prevalence of 26–201 cases per 100,000 persons. Incidence and prevalence are increasing worldwide; incidence is highest in North America and Northern Europe. Race: White >African American >Hispanic and Asian populations for risk.…

Risk 1:15,000-50,000 live births Most common human chromosomal syndrome Perioperative Risks Difficult airway management due to anatomic abnormalities of the airways. 30% can present with congenital heart disease. Aspiration risk. May require temp control. Cardiac events (pts may have cardiac…

Risk Iatrogenic transmission (actual and theoretical) Blood products: blood transfusion (3 reported cases). Greater risk with pooled products (since 1999 UK has imported blood fractions) or massive blood transfusion. Risk mitigated by deferral of recipients as donors (initiated: 1998 in…

Risk Pts with Hx of exposure to silica dust or PVC. Usual age group is 30–50 y. Fourfold to ninefold higher incidence in women than men; seen in all races. In USA systemic sclerosis has an estimated incidence of 19…

Risk Occurs in 1:2000-2500 live births. May be spontaneous, syndromic, or familial, but it most commonly presents as an isolated abnormality; however, it can present as a component of a syndrome or genetic disorder in 15–40% of pts. Familiarity with…

Risk Cleft lip and palates are the most common birth defects in USA. Cleft lip and/or palate incidence in USA is 1:600 newborns. Craniofacial clefts are rare, with incidence of 1:1000 births worldwide. Increased prevalence with Asians, Latinos, and Native…

Risk Disease affecting mostly middle- and old-aged men and postmenopausal women Gender difference: Higher incidence in women Periop CAS: Prevalent in elderly male pts with coronary risk factors Teenagers and young adults with illicit substance abuse, primarily cocaine Occurs in…