Tag Michelle S. Hirsch MD PhD

Cellular Angiofibroma

D efinition —A benign subcutaneous neoplasm composed of short fascicles of spindle cells with prominent small, thick-walled, blood vessels. Clinical Features Epidemiology Uncommon. Typically seen in middle-aged women (mean age ~55 years). You’re Reading a Preview Become a Clinical Tree…

Superficial Angiomyxoma

D efinition —A benign pedunculated myxoid soft tissue neoplasm with a tendency toward local recurrence. Clinical Features Epidemiology Rare. Occasionally occurs in the vulva. Most frequently seen in reproductive-age women in their 30s. You’re Reading a Preview Become a Clinical…

Aggressive Angiomyxoma

PITFALL D efinition —A bland, hypocellular, spindle cell lesion of the vulvar/perineal region with a tendency for local infiltration and recurrence. Clinical Features Epidemiology Reproductive-age women in their 30s. Uncommon. You’re Reading a Preview Become a Clinical Tree membership for…

Angiomyofibroblastoma

D efinition —A benign, nonrecurring spindle cell lesion of the vulvovaginal region, characterized by alternating hypercellular and hypocellular areas. Clinical Features Epidemiology Reproductive-age women. Uncommon. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Melanoma

D efinition —A highly malignant tumor of dermal melanocytes. Clinical Features Epidemiology Rare. Accounts for approximately 3% of all melanomas in women. The second most common vulvar malignancy. Most often in patients in their sixth decade of life. May be…

Dysplastic Nevus

D efinition —A melanocytic proliferation with architectural, cytologic, and clinical features that are intermediate between those seen in common nevi and melanoma. Clinical Features Epidemiology Patients have a higher risk of melanoma. Patients with first-degree relatives who have melanoma have…

Genital-Type Nevus

D efinition —A melanocytic proliferation seen in locations with redundant skin, characterized by large junctional melanocyte nests and transepidermal elimination of nests. Clinical Features Epidemiology Uncommon; estimated prevalence of 2.3% in women. Young women, most often in the third decade…

Lentigo

D efinition —Benign pigmented lesion of mucosal surfaces. Clinical Features Epidemiology No distinct demographic associations. Increased numbers may be seen in Carney complex. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…