D efinition — A human papillomavirus (HPV)–related exophytic lesion of the perianal skin and anal canal. Clinical Features Epidemiology Associated with low-risk HPV infection (types 6 and 11). Increased incidence with immunosuppression, including human immunodeficiency virus (HIV). Other risk factors…
D efinition —A rare, benign, spindle cell proliferation that occurs in the vulva of prepubertal women. Clinical Features Epidemiology Rare. Prepubertal women, age ranging between 4 and 12 years (median age is 8 years). You’re Reading a Preview Become a…
D efinition —A (usually) benign soft tissue tumor of the vulva of presumably neural crest lineage. Clinical Features Epidemiology Uncommon. Can occur at any age, with a mean age of presentation of 50 years. More common in African-American women. You’re…
D efinition —A discrete vascular ectasia with overlying epidermal hyperplasia. Clinical Features Epidemiology Typically seen in women under age 50. Typically sporadic but also associated with Fabry's disease (deficiency of lysosomal alpha-galactosidase). You’re Reading a Preview Become a Clinical Tree…
D efinition —A solitary, benign, polypoid lesion of the vagina composed of bland rhabdomyoblasts. Clinical Features Epidemiology Middle-aged women. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…
PITFALL D efinition —A malignant frequently biphasic tumor of soft tissue. Clinical Features Epidemiology Rare. Encountered in all age groups, mostly in the second and third decades. t(X:18) translocation (representing a fusion of SYT [at 18q11] with either SSX1 or…
D efinition —A malignant neoplasm of adipocytes. Clinical Features Epidemiology Rare. Most commonly encountered in middle-aged women. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…
D efinition —A benign adipocytic neoplasm. Clinical Features Epidemiology Rarely encountered in the vulva. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
D efinition —A painless, deep-seated, and slow-growing tumor with a deceptively bland histologic appearance and a propensity for local recurrence. Clinical Features Epidemiology Low-grade fibromyxoid sarcoma (LGFMS) is uncommon. Most often identified in children and young to middle-aged adults. The…
D efinition —A subcutaneous, locally aggressive spindle cell neoplasm with a storiform growth pattern and honeycomb-like infiltration into adipose tissue. Clinical Features Epidemiology Dermatofibrosarcoma protuberans involving the vulva is rare; however, cases have been reported. You’re Reading a Preview Become…