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D efinition —Human papillomavirus (HPV)–related proliferation of the vaginal mucosa that leads to extensive, full-thickness loss of maturation of the vaginal epithelium. Clinical Features Epidemiology Patients present at a slightly older age than those with cervical dysplasia, with the majority…

D efinition —Human papillomavirus (HPV)–related proliferation of the vaginal mucosa. Clinical Features Epidemiology Patients present at a slightly older age than those with cervical dysplasia, with the majority presenting around 40 years of age. Sixty-five percent of patients with vaginal…

PITFALL D efinition —Villiform remnants of hymenal ring. Clinical Features Epidemiology Typically seen in young women of reproductive age. No symptoms. Not related to human papillomavirus (HPV). You’re Reading a Preview Become a Clinical Tree membership for Full access and…

D efinition —A mass-forming, proliferative focus of misplaced endometrial glands and stroma within the vagina. Clinical Features Epidemiology Uncommon; vaginal endometriosis accounts for less than 10% of all endometriosis, with the most common form being traditional endometriosis composed of glands…

D efinition —Congenital glandular differentiation present within the vaginal mucosa. Clinical Features Epidemiology Prior to the use of diethylstilbestrol (DES) and in patients not exposed to DES the incidence of vaginal adenosis was rare. In patients who were exposed to…

D efinition —A fibrovascular response to injury comprised of small vascular structures, loose stroma, and admixed inflammation. Clinical Features Epidemiology Affects all age groups; vaginal granulation tissue is commonly seen after surgery in the vaginal cuff. You’re Reading a Preview…

D efinition —Protrusion of the fallopian tube into the vagina. Clinical Features Epidemiology Occasionally affects women after simple hysterectomy. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

D efinition —Infiltration of the perianal squamous epithelium by mucin-producing neoplastic cells associated with an anorectal neoplasm. Also called type 2 Paget's disease. Clinical Features Epidemiology Uncommon; represents only 1% to 2% of vulvar malignancies. The average age at presentation…

D efinition —Malignant tumors arising from the epithelium of the anal canal. Clinical Features Epidemiology Rare; incidence is estimated at 7 per million women and 9 per million men. Incidence is increasing at a rate of approximately 2% a year.…

D efinition —A high-grade, human papillomavirus (HPV)–associated, in situ lesion of the squamous anal mucosa. Clinical Features Epidemiology Associated with oncogenic HPV types (16 and 18). Increased risk with HPV, human immunodeficiency virus (HIV), anal intercourse, and multiple sexual partners.…