Category Pathology

Chronic Histiocytic Intervillositis

D efinition — Infiltration of the intervillous space by a monomorphic population of histiocytes. Clinical Features Epidemiology Uncommon. Histiocytic intervillositis is associated with spontaneous abortion and recurrent pregnancy loss. Rare cases of maternal malaria or recurrent sepsis have been documented.…

Chronic Villitis

D efinition — Maternal chronic inflammatory cells within terminal villi, not attributable to any known infection. Clinical Features Epidemiology Present in 5% to 10% of examined placentas. More often seen in women with autoimmune disorders such as systemic lupus erythematosus.…

Listeria Placentitis

PITFALL D efinition — Placental infection by the gram-positive bacteria Listeria monocytogenes . Clinical Features Epidemiology Placental infection with Listeria is an uncommon occurrence. The most common method of infection is ingestion of unpasteurized dairy products, although deli meats and…

Chorioamnionitis

D efinition — Ascending infection of the amniotic fluid leading to a fetal and maternal inflammatory response. Clinical Features Epidemiology Acute chorioamnionitis (ACA) is detected in approximately 25% of preterm deliveries, and gestational age of babies born with ACA is…

Amniotic Bands

D efinition — Detached strips of amniotic membrane that restrict fetal growth, resulting in asymmetric anomalies that do not follow a recognized developmental pattern. Clinical Features Epidemiology One in 2,500 to 10,000 deliveries. You’re Reading a Preview Become a Clinical…

Fetal Vascular Thrombosis

PITFALL D efinition — Thrombus formation within the umbilical cord, within its tributaries on the placental surface, or within stem villi. Clinical Features Epidemiology Common; seen in 3% to 10% of placentas. Increased incidence with maternal diabetes. You’re Reading a…