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D efinition — Umbilical cord with two vessels; one umbilical artery and one vein. Clinical Features Epidemiology Common; noted in 1% to 3% of all gestations. More frequent in spontaneous abortions. More frequent in white women than black or Asian…

D efinition — True knots in the umbilical cord. Clinical Features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

D efinition — Benign expansile nodule of capillaries and stromal cells. Clinical Features Epidemiology Uncommon; this finding is seen in less than 0.5% of placentas. Associated with twin gestations and preeclampsia. You’re Reading a Preview Become a Clinical Tree membership…

D efinition — A subset of extravillous trophoblastic tumor that is thought to arise from an extravillous (transitional) trophoblast that forms a transition from villous cytotrophoblast to mature extravillous trophoblast. These cells are found in the chorionic membrane, maternal surface…

D efinition — An abnormal early implantation site (IS) that can be identified in the setting of a molar pregnancy. Clinical Features Epidemiology Atypical molar ISs may be seen in the setting of any molar pregnancy. They are much more…

PITFALL D efinition —A malignancy that arises from the early implantation site extravillous trophoblasts. Clinical Features Epidemiology Placental site trophoblastic tumors (PSTT) are rare and were only recognized as a malignancy in 1981. PSTT are most commonly seen following a…

PITFALL D efinition — Choriocarcinoma occurring concurrently with a normal pregnancy. Clinical Features Epidemiology Intraplacental choriocarcinoma is exceedingly rare. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

D efinition — A trophoblastic malignancy composed of syncytiotrophoblasts and cytotrophoblasts, intermediate trophoblasts of both. Clinical Features Epidemiology At least half of choriocarcinomas follow a molar pregnancy, but only 2% to 3% of complete moles are followed by a diagnosis…

PITFALL D efinition — An abnormally large placenta characterized by striking, cystically dilated stem villi, stromal overgrowth, and hypervascularity. Clinical Features Epidemiology Rare; case reports only. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…