See also Tricyclic antidepressants General information Amineptine is a tricyclic antidepressant that selectively reduces the dopamine reuptake without affecting the uptake of noradrenaline or serotonin (5-HT) [ ]. In vivo, it increases striatal homovanillic acid concentrations without affecting the concentrations…
General information Amiloride is a potassium-sparing diuretic that acts in the distal convoluted tubule independently of the action of aldosterone, inhibiting sodium channels. It is a relatively safe drug with few reported adverse effects. Patients with congenital nephrogenic diabetes insipidus…
See also Aminoglycoside antibiotics General information Amikacin is a semisynthetic derivative of kanamycin with similar pharmacokinetic properties and dosages. It is resistant to many of the bacterial R factor-mediated enzymes that inactivate kanamycin and gentamicin. Noteworthy is its effect against…
See also Anorectic drugs General information Reports on the frequency of adverse reactions to amfepramone are not entirely consistent. The number of adverse effects reported by patients taking amfepramone closely paralleled the number in those taking placebo in one study…
See also Endothelin receptor antagonists General information Ambrisentan is an endothelin receptor antagonist that has been investigated in the treatment of idiopathic and secondary pulmonary hypertension [ ]. It is a propionic acid-based selective antagonist at endothelin type A (ET…
See also Herbal medicines Genera in the family of Amaryllidaceae ( Table 1 ) include the lily genus ( Allium ). This family includes genera that previously belonged to the family of Alliaceae. Table 1 Genera of Amaryllidaceae Allium (lily,…
See also Herbal medicines General information Genera in the family of amaranthaceae ( Table 1 ) include cotton flower and rockwort. Table 1 Genera of amaranthaceae Achyranthes (chaff flower) Cyathula (cyathula) Lithophila (lithophila) Aerva (aerva) Froelichia (snake cotton) Nototrichium (rockwort)…
General information Amantadine is a symmetrical C10 tricyclic amine with an unusual structure (1-adamantanamine hydrochloride). It interferes with virus uncoating [ ] by blocking the M2 ion channel, which is needed to affect a pH change that helps to initiate…
General information Alverine is a smooth muscle relaxant that is used to treat spasmodic conditions of the bowel [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you…
General information Aluminium is a metallic element (symbol Al; atomic no. 13), a light, silver-colored, malleable metal. Aluminium is the most abundant of all metals and is obtained from bauxite ores by the production of alumina, which is then smelted…