Category Internal Medicine

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General information Anecortave acetate is an angiostatic steroid derived from cortisol but without glucocorticoid receptor-mediated activity. It has been used in the treatment of neovascularization in age-related macular degeneration [ , ] and in glaucoma [ ]. It tends to…

See also Hormonal contraceptives—male General information The classic androgen is natural testosterone, which can be given orally in micronized form, but has much more often been used as the orally active 17-methyl derivative or an injectable ester. Androgens are used…

See also Interleukins General information Anakinra is an interleukin-1 receptor antagonist. It has been used to treat rheumatoid arthritis [ , ]. It has been tried in graft-versus-host disease, but without success [ ]. According to published trial data, moderate…

General information Anagrelide was developed as an inhibitor of platelet aggregation and acts by inhibiting phosphodiesterase. It was later found to reduce the platelet count, in doses lower than those required to inhibit platelet aggregation, by interfering with megakaryocyte differentiation…

See also Herbal medicines General information Genera in the family of Anacardiaceae ( Table 1 ) include pistachio, poison ivy, and sumac. Many yield foodstuffs, such as mangos, cashews, and pistachios, that can cause allergic reactions. Table 1 Genera of…

General information Amylin is a peptide hormone produced in the beta-cells of the islets of Langerhans and co-secreted with insulin. It has glucoregulatory effects that may complement the actions of insulin. Pramlintide is an amyloid analogue [ ]. It is…

General information Amygdalin is a glycoside that was initially isolated from the seeds of the almond tree Prunus dulcis ; it is also found in Prunus amygdala (bitter almond) [ ], Prunus armeniaca (apricot), Prunus serotina (black cherry) [ ],…

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See also Phosphodiesterase type III inhibitors General information Amrinone is an inhibitor of phosphodiesterase type III, and has a positive inotropic effect. Its adverse effects [ ] include thrombocytopenia (10%), hypotension, tachydysrhythmias (sometimes resulting in syncope and death) (9%), worsening…