Category Internal Medicine

Amphotericin

General information Having a broad-spectrum fungicidal activity, amphotericin remains the mainstay of treatment of most invasive fungal infections. Compared with conventional amphotericin B deoxycholate, other lipid formulations of amphotericin (amphotericin B colloidal dispersion, amphotericin B lipid complex, and liposomal amphotericin…

Amphetamines

General information Note on spelling In International Non-proprietary Names the digraph -ph- is usually replaced by -f-, although usage is not consistent, and -ph- is used at the beginnings of some drug names (for example, compare fenfluramine and phentermine) or…

Amoxapine

See also Tricyclic antidepressants General information Amoxapine has a tricyclic nucleus with a modified piperazine side chain and is closely related to the neuroleptic drug loxapine [ ]. In animals, amoxapine has no antiserotonergic properties and less anticholinergic activity than…

Amopyroquine

General information Amopyroquine is a 4-aminoquinoline, structurally related to amodiaquine. It is not a new compound, but it is of renewed interest as a result of the extensive occurrence of resistance to chloroquine and the adverse effects of prophylactic amodiaquine.…

Amodiaquine

General information Amodiaquine is a Mannich base derivative related to chloroquine. While it is generally considered equivalent to chloroquine, more recent studies have shown that amodiaquine is superior to chloroquine in tackling resistant strains of Plasmodium falciparum , although there…

Amlodipine

See also Calcium channel blockers General information Amlodipine is a long-acting dihydropyridine calcium channel blocker. It has an adverse effects profile similar to those of other dihydropyridines, but at a lower frequency [ ]. Along with felodipine [ ], but…