General information Almitrine is a respiratory stimulant that improves hypoxemia in about 80% of patients with severe chronic obstructive pulmonary disease [ ]. Oral almitrine bimesilate (100 mg/day) increased PaO 2 in patients with severe chronic obstructive pulmonary disease without…
General information Allopurinol is an inhibitor of xanthine oxidase, used to lower serum uric acid concentrations in the long-term treatment of gout and in the prevention of acute gout in people who are susceptible to hyperuricemia. Allopurinol is itself metabolized…
See also Cytotoxic and immunosuppressant drugs General information Alkylating cytostatic drugs include: Nitrosoureas: carmustine, lomustine, nimustine, streptozocin. N -lost derivatives: bendamustine, chlormethine, cyclophosphamide, estramustine. Others: busulfan, chlorambucil, dacarbazine, ifosfamide, melphalan, mitobronitol, mitomycin, procarbazine, thiotepa, temozolomide, treosulfan. The first two groups…
General information Alizapride is a substituted benzamide related to some neuroleptic drugs. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Renin inhibitors, direct General information Aliskiren is an orally active, non-peptidic inhibitor of renin, and is the only direct renin inhibitor approved for the treatment of hypertension. Its potential adverse effects and a comparison with other renin–angiotensin blockers…
General information The lower aliphatic alcohols (ethanol, isopropanol, 2-propanol, N -propanol, and 1-propanol) are widely used for skin antisepsis. In appropriate concentrations, these alcohols are bactericidal to most of the common pathogenic bacteria, but some rare species survive and can…
See also Antihistamines General information Alimemazine is a phenothiazine derivative with sedative antihistaminic and antimuscarinic effects. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…
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See also Alpha-adrenoceptor antagonists General information Alfuzosin is a uroselective alpha 1 -adrenoceptor antagonist used to relieve the symptoms of prostatic hyperplasia [ ]. Its safety has been investigated in a large prospective 3-year open trial in 3228 patients with…
See also Opioid analgesics General information Alfentanil is a potent short-acting opioid used in anesthesia. Beside its effects on opioid receptors, there is some evidence that it may affect acetylcholine, since intrathecal neostigmine produced a dose-dependent increase in the effect…