General information Aluminium is a metallic element (symbol Al; atomic no. 13), a light, silver-colored, malleable metal. Aluminium is the most abundant of all metals and is obtained from bauxite ores by the production of alumina, which is then smelted…
General information Alprostadil is PGE 1 available for exogenous administration. Alprostadil is widely used in neonates with cyanotic congenital heart disease to maintain the patency of the ductus arteriosus. Reported adverse effects include fever, apnea, flushing, bradycardia, and hyperostosis. Continuous…
General information Alprazolam, a triazolobenzodiazepine, has been marketed as an anxiolytic with additional antidepressant properties; an analogue, adinazolam, also has partial antidepressant activity [ ] and is useful in panic disorder. Like other benzodiazepines, alprazolam is effective in acute and…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information Alphaprodine is a synthetic opioid, structurally similar to pethidine. It is rapidly absorbed after oral submucosal injection [ ]. It has been used in pediatric dentistry, but it has been withdrawn from the market on a number of…
General information Alpha-glucosidase inhibitors are competitive inhibitors of 1α-glucosidases, enzymes that are located in the brush border of epithelial cells, mainly in the upper half of the small intestine. The enzymes degrade complex carbohydrates into monosaccharides, which are absorbed. The…
See also Individual agents General information The postsynaptic alpha-adrenoceptor antagonists, indoramin, prazosin, and related quinazoline derivatives, block alpha1-adrenoceptor-mediated vasoconstriction of peripheral blood vessels (both arterial and venous) and are effectively peripheral vasodilators [ , ]. Qualitatively and quantitatively common adverse…
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
General information Alpha 1 -antitrypsin is an alpha 1 proteinase inhibitor that neutralizes the activity of neutrophil elastase and is used to treat patients with homozygous deficiency of alpha 1 -antitrypsin [ ]. Adverse reactions occur only rarely [ ].…
See also Ondansetron and other 5HT 3 receptor antagonists Drug studies Placebo-controlled studies In a 12-week placebo-controlled study of alosetron 0.5 mg/day, 1 mg/day, or 1 mg bd in 705 women with severe diarrhea-predominant irritable bowel syndrome, all doses of…