Uropathology

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Lymphomas of the genitourinary organs

Definition Lymphomas, either primary or secondary, involving the genitourinary organs Clinical features Epidemiology Incidence is uncommon, accounting for less than 5% of extranodal lymphomas. Two-thirds are primary, and one-third are systemic lymphoma involving the genitourinary organs. The kidney is the…

Gastrointestinal stromal tumor of the genitourinary tract

Definition Gastrointestinal stromal tumors (GISTs) secondarily involving, or diagnosed on biopsy specimens of, the genitourinary tract Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Solitary fibrous tumor

Definition A fibroblastic mesenchymal neoplasm morphologically identical to its soft tissue counterpart Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Leiomyosarcoma of the bladder

Definition Malignant smooth muscle tumor of the bladder wall Clinical features Epidemiology Rare, but represents the most common malignant mesenchymal tumor of the bladder in adults Male predominance Most common in middle-aged to older patients Associated with acrolein, a degradation…

Leiomyoma of the bladder

Definition Benign smooth muscle tumor of the bladder wall Clinical features Epidemiology Rare, but represents the most common benign mesenchymal tumor of the bladder Female predominance Most common in middle-aged to older patients Rare in children You’re Reading a Preview…

Inflammatory myofibroblastic tumor of the bladder

Definition Myofibroblastic spindle cell neoplasm of uncertain malignant potential Clinical features Epidemiology Typically occurs in young adults (9–42 years old) Slight female preponderance History of recent prior instrumentation in a subset of cases You’re Reading a Preview Become a Clinical…

Staging for urethral carcinoma

Definition Staging system for penile carcinomas originating in the distal (penile) urethra You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Mucosal melanoma of the genitourinary system

Definition Primary melanoma originating from the mucosa of the genitourinary system Clinical features Epidemiology Rare, but more common in women (female/male=10:1) Incidence increases with age Most commonly involving urethra, penis, scrotum; rarely reported in prostate, bladder, and ureter Mean age,…