Tag Charles Guo MD

Mixed squamous cell carcinoma of the penis

Definition Squamous cell carcinoma (SCC) showing morphologic features of more than one histologic subtype in the same specimen Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you…

Primary urethral carcinoma

Definition Carcinoma arising from the urethral epithelium Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Epithelial tumors of the rete testis

Definition Neoplasms arising from the epithelial lining of the rete testis, ranging from benign (adenoma) to malignant (adenocarcinoma) Adenoma of the rete testis Clinical features Exceedingly rare Age range, 21–79 years Some patients have von Hippel-Lindau disease Appears as a…

Adenomatoid tumor

Definition A benign tumor of mesothelial origin in the testicular adnexa Clinical features Epidemiology The most common tumor in the testicular adnexa, including the epididymis, tunica albuginea, and spermatic cord Accounts for 32% of all tumors and 60% of all…

Prepubertal-type teratoma, testicular carcinoid tumor

Definition A monodermal teratoma in the prepubertal testis is composed of low-grade, well-differentiated neuroendocrine tumor (or carcinoid tumor). Although most cases are pure carcinoid tumor, some are mixed with epidermoid/dermoid cysts or other teratomatous components. Clinical features You’re Reading a…

Teratoma with somatic-type malignancies

Definition A teratoma develops a distinct secondary somatic (or non-germ cell) malignant component. Clinical features Epidemiology Only in postpubertal patients (age range, 15–68 years) Seen in 3%–6% of germ cell tumors (GCT) containing a teratomatous component You’re Reading a Preview…

Postpubertal-type teratoma

Definition GCT in the postpubertal testis composed of several types of somatic-type tissue originating from different germinal layers (endoderm, mesoderm, and ectoderm). It is usually composed of mature (or well-differentiated) tissues, and immature (or embryonic-type) tissues may be seen in…

Postpubertal-type yolk sac tumor

Definition Germ cell tumor (GCT) in the postpubertal testis composed of malignant epithelial cells recapitulating the extraembryonic structures, such as the yolk sac, allantois, and extraembryonic mesenchyma; also called endodermal sinus tumor Clinical features Epidemiology Patients are typically 15–40 years…

Embryonal carcinoma

Definition Germ cell tumor (GCT) composed of primitive epithelial tumor cells with marked nuclear atypia and indistinct cell borders, recapitulating an early phase of embryonic development Clinical features Epidemiology Affects young men with a peak age of 30 years, about…