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Fibrous, Fibrohistiocytic, and Fibrovascular Lesions The great majority of soft-tissue masses of the mouth are hyperplastic inflammatory responses to local, usually chronic, trauma or infection. Moreover, these reactive lesions are much more common in the mouth than in other parts…

Anatomy and Histology Nasal Cavity The nose is a complex organ composed of two components: the external and the internal nose. The external nose is triangular, with a wide base covering two external openings, the nares or nostrils, separated by…

Introduction Squamous cell carcinoma (SCC) of the upper aerodigestive tract (UADT) is the most common malignant neoplasm of the mucosal lining of the upper food and air passages. The estimated worldwide global annual burden of 630,000 new patients diagnosed resulting…

General Introduction There is considerable literature on all aspects of precursor lesions for squamous cell carcinoma of the upper aerodigestive tract (UADT). Most data are specific to oral and laryngeal lesions. A common feature of all these precursor lesions, irrespective…

Testicular cancer is the most common malignancy in men between the ages of 15 and 35 years, although this cancer accounts for less than 1% of all malignancies in men. The incidence of testicular cancer has steadily increased in recent…

Testicular specimens for non-neoplastic conditions are relative rarities in the surgical pathology laboratory. This chapter describes, illustrates, and compares the most common pathologic entities. Specimens may be obtained from patients who are newborn, prepubertal, or postpubertal. Therefore knowledge of the…

Diseases of the Penis Anatomy and Histology Anatomy plays a key role in the staging and understanding of neoplasms of the penis. Certain types of tumor are more likely to occur in specific anatomic sites. The three parts to the…

In the author’s surgical pathology practice at a large tertiary teaching medical center, the upper urinary tract specimens account for 5% to 10% of the genitourinary specimens. The major differences in clinical behavior and management between lesions of the upper…

Indication for Renal Biopsy The first aspiration renal biopsy was performed in 1944. The technique was introduced into clinical use in the early 1950s; however, only in the early 1960s was it considered a valuable and safe diagnostic procedure. The…

Renal Cell TUMORS Renal cell carcinomas are tumors that arise from or recapitulate the differentiation of the renal tubular epithelium. They are by far the most common renal cancers and account for more than 90% of all malignancies in the…