D efinition —An autoimmune blistering disorder that is the most common cause of subepidermal blisters. Caused by antibodies to a 230 kD plakin (BPAg1) and a 180 kD glycoprotein (BPAg2). Clinical Features Epidemiology Primarily seen in older patients and is commonly associated…
D efinition —Plasma cell–mediated vulvitis of unknown etiology. Clinical Features Epidemiology A rare condition. Has also been reported in men, as balanitis chronica circumscripta plasmacellularis. Age range is from 25 to 70 years, with middle-aged women most commonly being affected.…
D efinition —An uncommon idiopathic mucocutaneous inflammatory dermatosis with a prototypical lichenoid tissue reaction pattern, and a wide range of clinical presentations. Clinical Features Epidemiology Women at ages of 30 to 60 years. You’re Reading a Preview Become a Clinical…
D efinition —A chronic inflammatory dermatosis of unknown etiology that commonly affects the vulva. Clinical Features Epidemiology More commonly seen in perimenopausal and postmenopausal patients; however, can be seen at any age. Associations have been made with vulvar intraepithelial neoplasia…
D efinition —A chronic, recurrent dermatitis occurring in areas where sebum is produced marked by red plaques with a yellow scale. Clinical Features Epidemiology Common. Affects all demographic groups. Immunosuppressed patients and patients with some chronic conditions (including congestive heart…
D efinition —A chronic, hyperproliferative, papulosquamous disorder with a relapsing course. Clinical Features Epidemiology Affects 1% to 2% of Caucasians. Onset is usually in the late 20s. A genetic component is likely, as first-degree relatives are also often affected. At…
D efinition —A cutaneous reaction related to scratching, often superimposed on other dermatoses. Clinical Features Epidemiology Lichen simplex chronicus (LSC) is not a distinctive disease but a clinical and pathologic response to repeated physical trauma such as rubbing or scratching.…
D efinition —A constellation of inflammatory conditions caused by a reaction to exogenous or endogenous factors. Including, but not limited to, exogenous dermatitis, irritant contact dermatitis, allergic contact dermatitis, atopic dermatitis, and nummular dermatitis. Clinical Features Epidemiology Seen in all…
Introduction Head and neck specimens are technically difficult because they often comprise a lot of different anatomic structures and corresponding surgical margins. In the following text, some practical guidelines are given that may be useful when confronted with these specimens.…
A large array of pathologies must be considered in the differential diagnosis of symptoms affecting the ocular tissues. The major causes of conjunctival, orbital, and intraocular diseases, the histopathological findings, and major differential diagnoses are described in this chapter. A…