General information Fenspiride is a bronchodilator and anti-inflammatory drug. Two in vitro studies have suggested possible mechanisms for these effects. Functional studies in human isolated bronchi showed that fenspiride causes a shift to the left of concentration effect curves for…
See also Amphetamines , Anorectic drugs General information Fenproporex is structurally related to amfetamine, to which it is rapidly metabolized after oral ingestion. Stimulatory effects, somnolence, and electroencephalographic abnormalities are reported to be the major undesired reactions [ ]. Dependence…
See also Beta 2 -adrenoceptor agonists General information Fenoterol is a β 2 -adrenoceptor agonist with higher intrinsic activity than salbutamol; it produces a greater maximal effect and has greater systemic effects at higher than conventional doses. It is available…
General information Fenoldopam is a selective dopamine D 1 receptor agonist, which has been used in the management of acute severe hypertension and heart failure [ ], and to preserve renal function in various circumstances, such as after cardiac surgery…
See also Anorectic drugs ; Benfluorex ; Phentermine General information Although it resembles amfetamine structurally, the appetite suppressant fenfluramine does not produce central nervous system stimulation in therapeutic doses. Dexfenfluramine, the dextrorotatory isomer, was previously widely marketed as an appetite…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Fenclofenac was withdrawn in the UK after its licence was not renewed because of its adverse drug reactions profile [ ]. Data from the UK's Committee on Safety of Medicines included records…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information The profile of fenbufen is similar to the profiles of other NSAIDs [ ]. The dropout rate due to adverse reactions was 12–22% in different studies. Organs and systems Respiratory Fenbufen can…
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See also Calcium channel blockers General information Felodipine is a dihydropyridine derivative with diuretic properties [ ]. Its diuretic properties are not unique but are shared by other dihydropyridines. Vasodilatory adverse reactions include flushing, headache, and tachycardia [ , ].…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Felbinac, an active metabolite of fenbufen, is used as a gel for topical treatment and has been thought to be equivalent to ibuprofen [ ]. You’re Reading a Preview Become a Clinical…