General information Ezetimibe is a selective potent inhibitor of the intestinal absorption of dietary and biliary cholesterol. A total of 432 patients were included in a pooled analysis of two phase-II studies, both lasting for 12 weeks; ezetimibe was well…
General information Eyedrops and ointments are specialized pharmaceutical formulations intended to produce therapeutic concentrations of the active drug in ocular structures; a lower dose can be used than would be necessary to obtain the same effect by systemic administration. They…
General information Exenatide (synthetic exendin-4, from the saliva from a lizard) is an incretin mimetic [ ]. Incretins are compounds that increase insulin secretion from the pancreas in a glucose-dependent manner; they are therefore potential therapies for the treatment of…
General information Everolimus is an immunosuppressive macrolide that also has synergistic actions with ciclosporin and interrupts the proliferative responses of vascular and bronchial smooth muscle cells. In a phase I trial, its safety profile and pharmacokinetics were assessed during a…
General information The genera in the family of Euphorbiaceae ( Table 1 ) include various spurges, such as poinsettia and croton. Table 1 Genera of Euphorbiaceae Acalypha (copperleaf) Croton (croton) Mercurialis (mercurialis) Adelia (wild lime) Dalechampia (dalechampia) Pedilanthus (pedilanthus) Alchornea…
General information Etomidate, a non-barbiturate anesthetic, is considered to be safe, especially in patients with hemodynamic instability. The most common complications of using etomidate are venous sequelae, pain on injection [ ], and involuntary muscle movements [ ]. Organs and…
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Etodolac, a pyranocarboxylic acid, was first marketed in the UK in 1986. By 1988, etodolac had been reported 27 times to the UK Committee on Safety of Medicines as being suspected of…
General information Etifoxine is a non-benzodiazepine drug, licensed in France for psychosomatic manifestations of anxiety. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
General information Etidocaine is a highly lipid-soluble, long-acting aminoamide. It has a similar adverse reactions profile to that of bupivacaine and there is an increased risk of life-threatening cardiac events compared with lidocaine [ ]. You’re Reading a Preview Become…
General information Ethylenediamine is used to improve the solubility of theophylline in the formulation known as aminophylline (theophylline ethylenediamine). Aminophylline is converted to theophylline after oral and intravenous administration. Ethylenediamine is also used as a stabilizer in creams and ointments.…