See also Vitamins General information Pyridoxine (vitamin B 6 ) requirements vary with protein intake: the daily Average Requirement is 13 micrograms/g protein intake and the Population Reference Intake is 15 micrograms/g protein intake. In adults this translates into a…
See also Antituberculosis drugs General information Pyrazinamide is a pyrazine analogue of nicotinamide. It is bactericidal for Mycobacterium tuberculosis in an acid environment and in macrophages [ ]. Pyrazinamide passively diffuses into Mycobacterium tuberculosis , where pyrazinamidase (nicotinamidase) converts it…
General information Pyrantel is an antihelminthic drug that is effective against intestinal nematodes, including roundworms ( Ascaris lumbricoides ), threadworms ( Enterobius vermicularis ), Trichostrongylus species, and the tissue nematode Trichinella spiralis . Although it is effective against hookworms, it…
General information In 1957, psilocybin was isolated from the Psilocybe mexicana mushroom and it has since been identified as a component of over 75 distinct mushroom species [ ]. Psilocybin-containing mushrooms, also called “magic mushrooms”, are used recreationally, with an…
See also Xanthines General information Proxyphylline is a theophylline derivative used as a bronchodilator. It is readily absorbed from the gastrointestinal tract and is not converted to theophylline. Drug studies You’re Reading a Preview Become a Clinical Tree membership for…
See also Anesthetics, local General information Proxymetacaine (rINN) is a local anesthetic, an ester of meta-aminobenzoic acid. It is often used in ophthalmology. It is also known as proparacaine (USAN). Organs and systems You’re Reading a Preview Become a Clinical…
See also Individual agents General information Proton pump inhibitors inhibit the H + /K + -ATPase (proton pump) in oxyntic cells of the stomach, the final common pathway in the secretion of gastric acid in response to a variety of…
General information Protirelin is a synthetic tripeptide that stimulates the hypophyseal secretion of thyrotrophin (thyroid-stimulating hormone, TSH). It is used mainly for diagnostic purposes in dynamic tests of pituitary and hypothalamic function, but its use in the assessment of hyperthyroidism…
See also Coagulation proteins ; Drotrecogin General information Prothrombin complex products contain constant amounts of clotting factors II, VII, IX, and X, bypassing the need for factor VIII in the clotting cascade. They are used to reverse the effects of…
General information In addition to their natural occurrence, for example in cow’s milk, protein hydrolysates are added to hair-care products, such as shampoos and conditioners, and are supposed to “repair” damaged hair. Hydrolysed proteins are also used in other body-care…