General information Quinfamide is a dichloroacetyl quinolol that has been used as an amebicide [ ]. It acts on the trophozoites of Entamoeba histolytica , making the trophozoite incapable of propagation. It is not active against amebic cysts. In doses…
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See also Angiotensin-converting enzyme inhibitors General information The pharmacology, therapeutic uses, and safety of the ACE inhibitor quinapril have been reviewed [ ]. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…
General information Quinagolide is a non-ergot benzoquinoline dopamine D 2 receptor agonist. It has mainly been used to treat hyperprolactinemia [ , ], and also in Parkinson’s disease [ ], ovarian hyperstimulation syndrome [ ], and to suppress lactation […
General information The pharmacology, efficacy, and safety of quetiapine, an atypical neuroleptic drug, have been extensively reviewed [ ]. Quetiapine interacts with a broad range of neurotransmitter receptors and has a higher affinity for serotonin 5HT 2A receptors than dopamine…
See also Benzodiazepines General information Quazepam is a long-acting benzodiazepine with effects similar to those of diazepam. Organs and systems Nervous system The hangover effects of night-time administration of triazolam 0.25 mg, flunitrazepam 1 mg, and quazepam 15 mg were…
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General information Pyrrolizidine alkaloids occur in a large number of plants, notably the genera Crotalaria (Fabaceae), Cynoglossum (Boraginaceae), Eupatorium (Asteraceae), Heliotropium (Boraginaceae), Petasites (Asteraceae), Senecio (Asteraceae), and Symphytum (Boraginaceae) ( Table 1 ) [ ]. Table 1 Pyrrolizidine alkaloids in…
General information Pyritinol (pyridoxine disulfide or pyrithioxine) is a sulfhydryl-containing compound, a dimer of 5-thiopyridoxine. It was used from 1961 onwards as a psychostimulant of doubtful efficacy, but apparently without adverse reactions, and then largely abandoned. When it was re-introduced…
General information Pyrimethamine is the most active antimalarial of the 2–4-diaminopyrimidines, its effect being due to inhibition of the conversion of folic acid to its active form, folinic acid. It is also effective in toxoplasmosis. Its antiprotozoal and antimalarial activity…