See also Myeloid colony-stimulating factors General information Granulocyte colony-stimulating factor (G-CSF) primarily increases the production and function of neutrophils by stimulating the proliferation of committed myeloid precursors, rather than pluripotential stem cells [ ]. Recombinant human forms of G-CSF include…
General information Human chorionic gonadotropin (HCG, hCG), extracted from the urine of pregnant women, has mainly luteinizing hormone (LH) activity. Human menopausal gonadotropin (HMG, hMG) contains both follicle-stimulating hormone (FSH) and luteinizing hormone in about equal amounts. Where materials of…
General information The gonadorelin antagonists include abarelix, cetrorelix, degarelix, detirelix, ganirelix, iturelix, prazarelix, ramorelix, and teverelix. Gonadorelin agonists suppress the release of gonadotropin after an initial surge: pituitary suppression takes up to 2 weeks to develop. Competitive antagonists at gonadorelin…
General information Gonadorelin is gonadotropin-releasing hormone. The effects of gonadorelin depend on the duration of use. Gonadotropin release is stimulated in the short term, but is later suppressed owing to down-regulation of hypophyseal receptors. Its therapeutic indications have been summarized…
General information Gold is a heavy yellow-colored element (symbol Au; atomic no. 79). Its symbol derives from the Latin word aurum. It is usually found as the metallic element but can occur as salts such gold telluride (sylvanite). Auranofin is…
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General information Glycols are aliphatic dihydric alcohols. Primary and secondary glycols are thick liquids, and tertiary glycols (pinacones) are crystalline solids. The principal glycols to which people are or have been exposed, either occupationally or in medicinal products, are listed…
General information Glycine is an amino acid that is used in a 1.5% solution for bladder irrigation during transurethral prostatectomy and sometimes continuously for 24 hours after surgery. It has also been used to irrigate renal stone fragments after percutaneous…
General information Glycerol is a colorless syrupy liquid that is used medically as a laxative given orally, as an enema, or in the form of suppositories. Oral hypertonic glycerol has been used as a test for reversibility of the symptoms…
General information Aldehydes such as glutaral (glutaraldehyde), formaldehyde, and glyoxal are used as solutions and vapors for disinfection and sterilization. The safety and biocidal efficacy of glutaral has led to its endorsement by the CDC and WHO as a substitute…