General information All the HIV protease inhibitors have in common a specific effect against the aspartic HIV protease that cleaves viral proteins to yield structural proteins. Competitive inhibition of this process by the protease inhibitors results in the production of…
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General information The family of Hippocastanaceae contains the single genus Aesculus (buckeye, horse chestnut). Aescin is the major active principle from the horse chestnut tree ( Aesculus hippocastanum ) and is claimed to have clinical activity in venous insufficiency. Investigations…
General information Hexetidine has been used as an oral cavity antiseptic and in preventing plaque and gingival inflammation [ ]. At the concentration normally used (1 mg/ml), it is effective in vitro against Gram-positive bacteria and Candida albicans , but…
General information 1,2,6-hexanetriol is used as a humectant, solvent, and viscosity-controlling agent in medicaments and cosmetics. Some drug delivery systems involve the use of poly(ortho esters), prepared by the condensation of 1,2,6-hexanetriol and an alkyl orthoacetate [ ]. You’re Reading…
General information Hexachlorophene has been extensively used as an ingredient of innumerable kinds of consumer goods and medical formulations. Since 1961, when it was reported that daily bathing of newborn infants with a 3% hexachlorophene suspension prevented colonization of the…
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General information Members of the individual plant genera listed in Table 1 , based on the lists given in the Kew Herbarium Catalogue [ ], are covered in separate monographs. Each of the monographs has the following structure: Family: each…
General information Hepatitis A The successful propagation of hepatitis A virus in cell culture made the development of hepatitis A vaccines a realistic possibility. Various experimental hepatitis A vaccines have been tested in clinical trials. In December 1991, the first…