General information Edetic acid is a metal chelator. The effect of an intravenous dose of 1 g of calcium disodium edetate on the urinary excretion on the elements aluminium, boron, barium, calcium, copper, iron, lead, magnesium, manganese, phosphorus, potassium, silicon,…
General information The echinocandins are a class of semisynthetic antifungal lipopeptides that are structurally characterized by a cyclic hexapeptide core linked to a variably configured lipid side chain. The echinocandins act by non-competitive inhibition of the synthesis of 1,3-α- d…
General information Ecabet is an anti-ulcer agent that works by irreversibly inhibiting urease and ATPase in Helicobacter pylori under acidic conditions [ , ]. It may also impair bacterial adhesion to gastric epithelia [ ]. It has bactericidal activity against…
See also Antihistamines General information Ebastine is a second-generation antihistamine with proven efficacy in the treatment of allergic disease [ ]. It is rapidly absorbed after oral administration, and undergoes extensive first-pass metabolism by CYP3A4 to its active carboxylic acid…
See also Antiandrogens General information Dutasteride (Avodart®) inhibits both types 1 and 2 and is approved for the treatment of symptomatic benign prostatic hyperplasia in a dose of 0.5 mg It is about three times more potent than finasteride at…
General information Duloxetine is an antidepressant that inhibits the reuptake of both serotonin (5HT) and noradrenaline [ ]. Drug studies Placebo-controlled studies In a placebo-controlled study of 1491 patients nausea was more frequent in those who took duloxetine (30% versus…
General information The genera in the family of Dryopteraceae ( Table 1 ) include various types of fern. Table 1 Genera of Dryopteraceae Arachniodes (holly fern) Athyrium (ladyfern) Bolbitis (creeping fern) Ctenitis (lacefern) Cyclopeltis (cyclopeltis) Cyrtomium (netvein hollyfern) Cystopteris (bladderfern)…
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General information The protein C pathway serves as a natural defence mechanism against thrombosis. Patients with severe sepsis have a very low concentration of activated protein C compared with healthy individuals. Protein C is available as either a concentrate prepared…
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