See also Neuroleptic drugs General information Droperidol is a butyrophenone with actions similar to those of haloperidol. Of 20 volunteers who took droperidol 5 mg orally in orange juice, none had a neutral or pleasant experience [ ]. All reported…
See also Antihistamines ; Dicycloverine General information Doxylamine is an antihistamine, a monoethanolamine derivative, with antimuscarinic and pronounced sedative effects. Organs and systems Nervous system Giddiness and drowsiness were reported in adults taking Vicks Medinite syrup (doxylamine + dextromethorphan +…
See also Tetracyclines General information Doxycycline and minocycline are more lipophilic tetracyclines. They are well absorbed after oral administration. Their half-lives are 16–18 hours. Their higher affinity for fatty tissues improves their effectiveness and changes their adverse effects profile. Local…
See also Cytotoxic and immunosuppressant drugs General information Doxifluridine is a derivative of 5-fluorouracil. It has been used to treat a variety of solid tumors, including cancers of the breast, pancreas, stomach [ ], and large bowel. You’re Reading a…
See also Tricyclic antidepressants General information Doxepin is a tricyclic antidepressant that has also been used topically in the treatment of atopic dermatitis and other forms of eczematous dermatitis. It causes the adverse effects that one would expect, and systemic…
See also Alpha-adrenoceptor antagonists General information The α 1 -adrenoceptor antagonist doxazosin has similar adverse effects to those of prazosin. In a review of its clinical pharmacology and therapeutic uses, reports of tolerability included an update from previously unpublished pooled…
General information Generalized stimulation of the central nervous system has been observed with doxapram, particularly in large doses. Adverse reactions have included hyperactivity, tachycardia, increased deep tendon reflexes and muscle twitching, and laryngospasm. Raised blood pressure can also occur. Doxapram…
General information Doxacurium chloride is a long-acting non-depolarizing neuromuscular blocking agent. It is a bisquaternary benzylisoquinolinium derivative (a diester). It is subject to minimal hydrolysis by plasma cholinesterase (at about 6% of the rate of hydrolysis of suxamethonium when incubated…
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General information Dornase alfa is human recombinant deoxyribonuclease. Daily therapy with dornase alfa in patients with cystic fibrosis can reduce the frequency of respiratory infections and improve lung function in patients with bronchiectasis. You’re Reading a Preview Become a Clinical…