General information Tyrosine kinase inhibitors are effective in the targeted treatment of various malignancies. Imatinib was the first to be introduced into clinical oncology, and it was followed by drugs such as erlotinib, gefitinib, sorafenib, sunitinib, and dasatinib. Although they…
General information The genera in the family of Ericaceae ( Table 1 ) include heather, huckleberry, and rhododendron. Table 1 Genera of Ericaceae Agarista (Florida hobblebush) Epigaea (trailing arbutus) Menziesia (menziesia) Andromeda (bog rosemary) Erica (heath) Ornithostaphylos (ornithostaphylos) Arbutus (madrone)…
General information The ergot alkaloids are dopamine receptor agonists. Ergot derivatives include ergotamine tartrate, dihydroergotamine, ergometrine (also called ergonovine), and methylergotamine (also called methylergonovine). They are potent α 1 -adrenoceptor and 5-HT receptor antagonists. Ergotamine and dihydroergotamine Ergotamine and dihydroergotamine…
General information Eptifibatide is a glycoprotein IIb/IIIa inhibitor. Drug studies Comparative studies In a systematic review of comparisons of eptifibatide (n = 2812) and abciximab (n = 729), there were no differences in the incidences of in-hospital death (4.1% with…
General information Eprozinol hydrochloride inhibits bronchoconstriction by an action on histamine H 1 receptors [ , ] and has been used in the treatment of asthma and bronchitis. You’re Reading a Preview Become a Clinical Tree membership for Full access…
See also : Angiotensin II receptor antagonists General information Eprosartan is a non-biphenyl, non-tetrazole competitive antagonist at angiotensin II type 1 (AT1) receptors that is chemically distinct from other angiotensin II receptor antagonists [ ]. It causes dual blockade of…
General information Eprazinone hydrochloride is a cough suppressant that is also reported to have expectorant properties. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…
See also Prostaglandins General information Epoprostenol is PGI 2 available for exogenous administration. It has become the preferred long-term treatment for patients with primary pulmonary hypertension who continue to have symptoms in spite of conventional therapy. However, tolerance, which always…
General information Eplerenone is a potassium-sparing diuretic. It is similar to spironolactone as an aldosterone antagonist, but has less affinity for androgen and progesterone receptors and may therefore have fewer adverse effects [ ]. Eplerenone is metabolized by CYP3A4 […
General information Ephedra consists of a mixture of different members of the Ephedraceae family ( E. sinica , E. equisetina , and E. gerardiana ). Its actions are due to the presence of ephedrine and pseudoephedrine. Both ephedrine and pseudoephedrine…