Definition Germ cell tumors showing trophoblastic differentiation other than choriocarcinoma and non-trophoblastic tumors with syncytiotrophoblasts, including placental trophoblastic tumor (PSTT), epithelioid trophoblastic tumor (ETT) and cystic trophoblastic tumor (CTT) Clinical features You’re Reading a Preview Become a Clinical Tree membership…
Definition Complete filling of seminiferous tubules by neoplastic germ cells, including seminoma and other non-seminomas Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…
Definition Decreased production or delivery of spermatozoa or production of abnormal spermatozoa Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Definition Retroperitoneal fibrosis encompasses a spectrum of inflammatory and fibrosing diseases involving the retroperitoneal structures. Etiology not clearly understood in 2/3 cases; hence, idiopathic retroperitoneal fibrosis (IRF) Some studies argue that IRF is part of the spectrum of IgG4-related disease.…
Definition Encompasses a spectrum of biphasic tumors composed of variable amounts of epithelial and stromal components, ranging from predominantly cystic tumors (adult cystic nephroma, CN) to variably solid tumors (mixed epithelial and stromal tumor, MEST) Clinical features Epidemiology Adult patients…
Definition Angiomyolipoma (AML) composed predominantly, at least 80%, of epithelioid cells Clinical features Epidemiology Eight percent of AMLs in surgical cohorts have an epithelioid component (10% or more of the tumor). Mean age, 50 (range 30–80) years Both genders are…
Definition A benign tumor recapitulating differentiation toward early embryonic metanephric tubules; also known as embryonal adenoma or nephrogenic nephroma Clinical features Epidemiology Female predominance Wide age range, from infants to elder individuals You’re Reading a Preview Become a Clinical Tree…
Definition A group of recently described renal cell carcinomas with morphology similar to tumors in patients with tuberous sclerosis complex (TSC) and harboring somatic mutations in the genes of the TSC and mTORC1 pathways. They may have diverse morphological patterns.…
Definition A recently described variant of renal cell carcinoma (RCC) defined morphologically by solid and cystic areas composed of tumor cells with voluminous eosinophilic cytoplasm and basophilic coarse cytoplasmic granules and positive cytokeratin 20 staining Clinical features Epidemiology Incidence currently…
Definition A group of renal cell carcinoma (RCC) with prominent smooth muscle–rich stroma that invests tumor cells, probably a heterogeneous group of RCCs with similar morphology. Considered an emerging/provisional entity in the World Health Organization (WHO) classification Clinical features Epidemiology…