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Definition Lymphomas, either primary or secondary, involving the genitourinary organs Clinical features Epidemiology Incidence is uncommon, accounting for less than 5% of extranodal lymphomas. Two-thirds are primary, and one-third are systemic lymphoma involving the genitourinary organs. The kidney is the…

Definition Primary melanoma originating from the mucosa of the genitourinary system Clinical features Epidemiology Rare, but more common in women (female/male=10:1) Incidence increases with age Most commonly involving urethra, penis, scrotum; rarely reported in prostate, bladder, and ureter Mean age,…

Definition Aggressive neoplasm of neuroendocrine differentiation, identical to its cutaneous counterpart Clinical features Epidemiology Primary Merkel cell carcinoma of the genitourinary (GU) tract extremely rare, with single case reports in the vulva, vagina, penis, and scrotum Patient age between third…

Definition A form of penile squamous cell carcinoma (SCC) with both squamous and adenocarcinomatous components, probably arising from the embryologically misplaced glands or metaplastic mucinous glands Clinical features Epidemiology Non-HPV related Rare Similar to usual SCC You’re Reading a Preview…

Definition A form of squamous carcinoma with exophytic and papillomatous growth pattern resembling condylomas but with malignant cytological features Strongly associated with high-risk human papillomavirus infection Clinical features Epidemiology 5%–10% of penile carcinomas and 20%–30% verruciform tumors Most commonly involves…

Definition Nonneoplastic proliferation of fibrous tissue admixed with inflammatory cells frequently involving the tunica vaginalis Clinical features Epidemiology Most common in the third through sixth decades of life Associated with a hydrocele in 50% of cases Prior trauma or inflammation…

Definition A vestigial remnant of the Müllerian duct present on the upper pole of the testis and attached to the tunica vaginalis; also called hydatid of Morgagni Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full…

Definition A testicular stromal tumor showing features of intertubular primitive mesenchymal cells and peritubular myoid cells Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Definition A germ cell tumor that predominantly affects young children and recapitulates the extraembryonic structures including the yolk sac, allantois, and extraembryonic mesenchyme Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Definition Germ cell tumors that are partially or completely regressed, resulting in a scar or fibrotic area in the testis. Also known as “burned-out” germ cell tumors. Clinical features Epidemiology Partial or complete spontaneous regression occurs in <5% of germ…