Eosinophilic solid cystic renal cell carcinoma


  • A recently described variant of renal cell carcinoma (RCC) defined morphologically by solid and cystic areas composed of tumor cells with voluminous eosinophilic cytoplasm and basophilic coarse cytoplasmic granules and positive cytokeratin 20 staining

Clinical features


  • Incidence currently unknown but rare; many were diagnosed as “unclassified RCC” or “unclassified renal oncocytic tumors”

  • ~10% occur in patients with tuberous sclerosis complex (TSC); majority sporadic

  • Mean age: 55 (range, 32–79) years

  • Female predilection with only rare cases reported in men

You're Reading a Preview

Become a Clinical Tree membership for Full access and enjoy Unlimited articles

Become membership

If you are a member. Log in here