Definition A variant of renal cell carcinoma (RCC) defined by the loss of protein expression of succinate dehydrogenase B on immunohistochemistry Clinical features Epidemiology Rare, <0.2% of all RCCs Mean age, 38 years (range, 14–76) Male to female ratio, 1.8:1 Majority…
Definition Subtype of renal cell carcinoma harboring gene fusions involving two members of MiT family transcription factors, TFE3 (with Xp11 translocation), and TFEB (with t(6;11) translocation) Clinical features Epidemiology The majority of cases are reported in children and young adults.…
Definition A variant of renal cell carcinoma defined by loss of protein expression of fumarate hydratase (FH) on immunohistochemistry; the majority of tumors occur in the setting of hereditary leiomyomatosis and renal cell carcinoma syndrome (HLRCC) with germline mutation in…
Definition The most common histological subtype of renal cell carcinoma (RCC), composed of cells with clear or eosinophilic cytoplasm and a prominent but delicate vascular network Clinical features Epidemiology Two percent of all malignancies and approximately 70% of RCCs Primarily…
Definition Development of bilateral and multiple renal cysts in patients whose chronic renal failure cannot be attributed to a hereditary etiology Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…
Definition Cystic dilatation of papillary collecting ducts of one or more renal pyramids Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
Definition Localized cystic disease (LCD) involves part of a, or rarely entire, kidney with multiple cysts surrounded by normal renal parenchyma. Also known as unilateral cystic disease or segmental cystic disease. Clinical features Epidemiology Rare Median age 33.3 (range 18–56)…
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Definition Neoplasm derived from the paraganglial cells in the bladder wall Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
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