D efinition — The histologic appearance of large prostatic duct–like tissue within the cervical stroma. Clinical Features Epidemiology Prostatic metaplasia is a rare (or possibly under-reported) process. There is no age predilection. You’re Reading a Preview Become a Clinical Tree…
D efinition — A carcinoma derived from mesonephric remnants located in the lateral walls of the uterine cervix. Clinical Features Epidemiology Very rare. The mean age at presentation is early 50s. You’re Reading a Preview Become a Clinical Tree membership…
D efinition — Embryologic remnants of mesonephric differentiation found in the gynecologic tract. Clinical Features Epidemiology Mesonephric remnants may be identified in up to one fifth of well-sampled cervices. No age or demographic predilection has been identified. You’re Reading a…
D efinition — Adenocarcinoma composed of basaloid cells with areas of columnar cell differentiation. Clinical Features Epidemiology Rare; accounts for less than 5% of cervical carcinomas. Usually seen in postmenopausal women. Human papillomavirus (HPV) associated. African-American women are affected more…
D efinition — A rare variant of invasive adenocarcinoma originating in the endocervix. Clinical Features Epidemiology Limited to case reports. Wide age range, but most present in the fourth or fifth decade. Human papillomavirus (HPV) associated. May be found with…
D efinition — A carcinoma resembling an upper genital tract serous carcinoma but originating in the cervix and usually human papillomavirus (HPV) related. Clinical Features Epidemiology Rare. There is a distinctly bimodal age distribution; most patients are under age 45,…
D efinition — A deceptively bland-appearing mucinous adenocarcinoma of the cervix. Atypical lobular endocervical glandular hyperplasia (ALGH) is considered a potential precursor to minimal deviation adenocarcinoma (MDA). Clinical Features Epidemiology Uncommon. Not associated with human papillomavirus (HPV). Reproductive-age women; mean…
D efinition —A unique, typically HPV-negative adenocarcinoma that has been associated with prenatal diethylstilbestrol exposure. Clinical Features Epidemiology Rare. Historically linked to diethylstilbestrol (DES) exposure in utero. Sporadic occurrences now much more frequent than DES-related cases. Wide age range, with…
D efinition — Invasive adenocarcinoma originating in the endocervix. Clinical Features Epidemiology Average age at diagnosis is early 40s. Human papillomavirus (HPV) associated. A positive association with oral contraceptive use has been noted, but the mechanism is not understood. Not…
D efinition —A florid pattern of endocervical adenocarcinoma in situ (AIS) that mimics invasive adenocarcinoma. Clinical Features Epidemiology The same as for conventional AIS. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…