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D efinition —Alterations in the endometrium due to lack of ovulation and estrogenic effects of a persistent follicle. Clinical Features Epidemiology Most commonly seen at or around menopause with failed ovulation and persistent follicle. Common in polycystic ovarian syndrome (PCOS).…

D efinition — Scheduled menstrual breakdown and abnormal stromal breakdown histologically mimicking adenocarcinoma. Clinical Features Epidemiology The presence of stromal breakdown within an endometrial biopsy is relatively common; fortunately, however, extensive breakdown, mimicking neoplasia, is relatively uncommon. You’re Reading a…

D efinition — Bleeding that occurs in the absence of ovulation and is not associated with an endometrial structural abnormality or other visible cause (fibroid or polyp). Clinical Features Epidemiology Dysfunctional uterine bleeding (DUB) is common, more frequently seen near…

D efinition — A polyp of the cervix composed of mature glial tissue. Clinical Features Epidemiology Extremely rare. Signifies retained glial tissue from a prior pregnancy based on genetic studies. Reproductive age group. You’re Reading a Preview Become a Clinical…

D efinition — A generally benign, peripheral nerve sheath tumor. Clinical Features Epidemiology Rare, limited to occasional case reports. Most reported cases—benign and malignant—occur in the third to eighth decades. You’re Reading a Preview Become a Clinical Tree membership for…

D efinition — A proliferation of specialized cuboidal cells derived from the squamocolumnar junction that gives rise to reserve cells, squamous metaplasia, and can harbor squamous intraepithelial lesions (SILs). Clinical Features Epidemiology Most commonly occurs in young women with an…

D efinition — A benign, discrete proliferation of smooth muscle stroma and endocervical glands. Clinical Features Epidemiology Adenomyomas and polypoid adenomyomas of the cervix are rare. The majority of these lesions occur within the uterine cavity, not at the cervix.…

D efinition — Endometrial adenocarcinoma which has spread caudally to involve the cervix. Clinical Features Epidemiology Varies with the subtype of endometrial adenocarcinoma. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…

D efinition — Serous carcinoma originating from the upper genital tract involving the cervix (drop metastasis). Clinical Features Epidemiology Uncommon. Women in their 60s to 70s. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…

D efinition — An increase in the number of endocervical glands. May be idiopathic or secondary to increased hormonal stimulation. Some atypical hyperplasias may be associated with minimal deviation adenocarcinomas and Peutz-Jeghers syndrome (see page 300 ). Clinical Features Epidemiology…