Uses Treatment of: Insomnia (valerian is present in virtually all herbal sleep aids) Anxiety Depression Htn GI hyperactivity Headaches Muscle spasms Benzodiazepine withdrawal Perioperative Risks Potential for valerian withdrawal exists if usage is stopped suddenly after chronic high-dose administration. This…
Uses More than 3% of presurgical pts report using St. John’s wort. Taken mainly for depression, although pts may take it for a variety of reasons including anxiety, viral and bacterial infections, menstrual cramps, HIV, cancer, chest congestion, hemorrhoids, skin…
Uses Naturally occurring in human diet. Used as supplements, especially in margarines, to reduce cholesterol levels. May also possess anti-inflammatory, antipyretic, antineoplastic, and immune-modulating properties. Some recent evidence questions the beneficial effect of phytosterols and the potential for increased CV…
Uses Medical: Historically used to lower cholesterol and treat rare conditions of heart failure due to creatine deficiencies; it has proposed benefits to decrease myalgias and myositis with statins. Fitness: Increased usage of creatine over past decade to increase muscle…
Uses Body building (ineffective) May aid in glycemic control of type II DM and gestational DM Hyperlipidemia Hypoglycemia (reactive) Obesity Perioperative Risks Risks minimal Chronic ingestion associated in one case with thrombocytopenia, hepatic dysfunction, renal dysfunction You’re Reading a Preview…
Uses Management of thromboembolic disorders: For prophylaxis, Rx, and prevention of recurrence of thromboembolic events including DVT, pulm embolism, thrombosis of grafts. Prevention of arterial emboli associated with prosthetic heart valves, nonvalvular AFib, acute MI. Prevention of MI, stroke, and…
Uses Rescue of primary immunosuppressant Rx following liver, lung, heart, pancreas, and limb transplant. Approximate number of candidates: 3000 awaiting liver transplant and 9000 awaiting kidney transplant in USA; 15,000 living liver transplant and 50,000 kidney transplant recipients are chronically…
Uses Treatment of erectile dysfunction (Viagra) Sildenafil (Revatio) is used to improve the ability to exercise in people with pulm arterial Htn Oral sildenafil is used as part of multimodal management of severe periop pulm Htn and right ventricular dysfunction…
Uses Critical components in treatment algorithm for invasive and/or in situ breast cancer, breast cancer chemoprevention in high-risk pts, and postmenopausal osteoporosis (raloxifene only) Perioperative Risks VTE, particularly if the pt has a history of recent chemotherapy, prior irradiation, or…
Uses Therapy for MG, which is caused by decreased postsynaptic ACh receptors. Antagonism of nondepolarizing NMBDs. Therapy for glaucoma. Therapy for atony of GI and urinary tracts. Perioperative Risks Muscarinic effects on GI, respiratory, and CV systems. Prolonged response to…