Tag Lee A. Fleisher

Pseudoephedrine

Uses An OTC sympathomimetic commonly used as a nasal decongestant or for opening obstructed eustachian ostia. Used in the symptomatic treatment of reactive airway disease; however, appears to be ineffective as a bronchodilator. Also used for treatment of ejaculatory dysfunction…

Phenytoin

Uses Management of generalized tonic-clonic (grand mal) and complex partial seizures Prophylaxis against seizures after trauma or surgical intervention Treatment of ventricular arrhythmias, especially those associated with digitalis or tricyclic antidepressant toxicity Treatment of prolonged QT interval Treatment of epidermolysis…

Nitroglycerin

Uses Therapy for pts with angina. CHF In MI, can reduce infarct size. Prinzmetal angina. Can be given as a patch, paste, or pill taken sublingually as needed. Uterine relaxation for retained placenta, although a systematic review did not demonstrate…

Leukotriene Antagonists

Uses Include the leukotriene receptor antagonists montelukast, zafirlukast, and pranlukast (not available in USA) as well as the 5-lipoxygenase (5-LO) inhibitor zileuton. Montelukast is the most commonly used drug of this class in USA. Montelukast is a once-daily oral drug…

Cromolyn Sodium

Uses Approved by the FDA in 1973 as the first prophylactic nonsteroidal drug available for treatment of chronic asthma. Alternative initial maintenance therapy for mild persistent and moderate persistent asthma. Preventative only; not effective during acute episodes of bronchospasm. Beneficial…

Aspirin (Acetylsalicylic Acid)

Uses People in USA consume 10,000–20,000 tons annually. Rx for mild and/or moderate pain, fever, arthritis, and prevention of MI. Perioperative Risks Peptic ulcer disease Plt dysfunction Increased bleeding risk Stroke Interstitial nephritis Reye syndrome Worry About Displacement of protein-bound…

Antianxiety Medications

Uses Preop anxiolysis, anterograde amnesia, IV sedation, IV induction of anesthesia, suppression of seizure activity, muscle relaxation Perioperative Risks Sedation Respiratory depression Apnea Airway obstruction Delayed emergence Delirium Worry About Potentiation of respiratory depression with opioids You’re Reading a Preview…

ACE Inhibitors

Uses Treatment of essential Htn, CHF, and mitral regurgitation. Numerous studies show that ACE-I use improves symptoms and quality of life, as well as reduces mortality rate in elderly with heart failure and decreased LVEF. Decreases mortality after myocardial infarction.…

Varicella-Zoster Virus

Risk Prevalence: <10% of adults seronegative Usually contracted during childhood. Perioperative Risks Minimal additional risk to pts unless immunocompromised. Risk of infection for caregivers. Worry About Encephalitis in immunocompromised pt Potential nosocomial transmission Acyclovir-induced nephrotoxicity Transmission to pregnant woman Overview…