Embryonal carcinoma


Definition

  • Germ cell tumor (GCT) composed of primitive epithelial tumor cells with marked nuclear atypia and indistinct cell borders, recapitulating an early phase of embryonic development

Clinical features

Epidemiology

  • Affects young men with a peak age of 30 years, about 10 years younger than seminoma

  • Rare in prepubertal children

  • Common as a component of mixed GCTs; present in 40% of all mixed GCTs

  • Rare in pure form, comprising 2%–16% of all GCTs

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