• Germ cell tumor (GCT) composed of uniform malignant cells with clear cytoplasm and large round nuclei that are considered the neoplastic counterparts of the primordial germ cells (or gonocytes) during early embryonic development

Clinical features


  • Patient mean age, 40 years; about 10 years older than patients with non-seminomatous GCT

  • Not seen in prepubertal children except for children with a disorder of sex development

  • The most common histologic type of testicular GCT

  • Pure seminoma accounts for 50% of all testicular GCT.

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