General information Piperaquine is a synthetic 4-aminoquinoline with high blood schizonticidal activity, similar to that of chloroquine [ ]. It was developed in the 1960s by Shanghai Pharmaceutical Industry Research (China) and Rhone Poulenc (France) and has been combined with…
General information The family of Piperaceae contains three genera: 1. Lepianthes (lepianthes) 2. Peperomia (peperomia) 3. Piper (pepper) Piper methysticum Kava or awa ( Piper methysticum ) is a plant that grows in the South Pacific Islands. Eight species have…
General information Pipecuronium bromide is a bisquaternary steroid analogue of pancuronium. In vitro pipecuronium reversibly inhibits both human red cell acetylcholinesterase and human plasma cholinesterase to an extent that might have clinical implications [ ]. Its potency is similar to…
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See also Beta-adrenoceptor antagonists General information Pindolol is a beta-adrenoceptor antagonist with β 2 -adrenoceptor agonist action and some membrane-stabilizing activity [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…
See also Anticholinergic drugs General information Pinaverium bromide is an anticholinergic drug [ ]. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Neuroleptic drugs General information Pimozide is a diphenylbutylpiperidine neuroleptic drug, structurally similar to the butyrophenones. Organs and systems Cardiovascular Pimozide can cause QT interval prolongation and torsade de pointes; a total of 40 cases (16 deaths) of serious…
See also Phosphodiesterase type III inhibitors General information Pimobendan is an inhibitor of phosphodiesterase type III with calcium-sensitizing properties in the myocardium. It has been associated with a worrisome albeit non-significant increase in mortality in patients with chronic congestive heart…
General information Pimecrolimus is a non-steroidal ascomycin derivative with topical anti-inflammatory activity. In a 1% cream it is effective and safe in atopic dermatitis in infants, children, and adults [ ], although its efficacy has been questioned [ ]. You’re…
See also Antidysrhythmic drugs General information Pilsicainide is a class Ic antidysrhythmic drug, which blocks the fast inward sodium channel and is used to treat supraventricular and ventricular tachycardias [ ]. Drug studies Observational studies In 40 patients with paroxysmal…