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General information Pleconaril is an antiviral drug, effective against picornaviruses, including non-polio enteroviruses [ ] and rhinoviruses [ ]. In 2002 the US FDA refused to license pleconaril because of adverse reactions, of which the most commonly reported were mild…
See also Cytotoxic and immunosuppressant drugs General information Although the main platinum-containing cytotoxic drugs, cisplatin, carboplatin, and oxaliplatin, share some structural similarities, there are marked differences between them in therapeutic uses, pharmacokinetics, and adverse effects profiles [ ]. Compared with…
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General information Plasma products are used to substitute plasma proteins and in plasma exchange. Fresh frozen plasma is used as a source of coagulation factors in deficiency, if no purified factors are available. Intensive plasma exchange has been studied in…
General information The family of Plantaginaceae contains two genera: 1. Littorella (littorella) 2. Plantago (plantain) You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…
General information Plague vaccine is a suspension of the formaldehyde-killed encapsulated form of Yersinia pestis . Primary immunization involves three doses given intramuscularly. The Working Group on Civilian Biodefense has developed consensus-based recommendations for measures to be taken by medical…
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See also Antihistamines General information Pizotifen is a 5HT receptor antagonist chemically related to the tricyclic antidepressants, with a five-membered third ring containing a sulfur atom. It has been suggested that adverse reactions to pizotifen resemble those of amitriptyline […
See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Pirprofen is a non-steroidal anti-inflammatory drug, a phenylpropionic acid derivative. It has been used to treat rheumatoid arthritis [ ], osteoarthritis [ ], and ankylosing spondylitis [ , ], and as an…