Category Internal Medicine

Pleconaril

General information Pleconaril is an antiviral drug, effective against picornaviruses, including non-polio enteroviruses [ ] and rhinoviruses [ ]. In 2002 the US FDA refused to license pleconaril because of adverse reactions, of which the most commonly reported were mild…

Platinum-containing cytostatic drugs

See also Cytotoxic and immunosuppressant drugs General information Although the main platinum-containing cytotoxic drugs, cisplatin, carboplatin, and oxaliplatin, share some structural similarities, there are marked differences between them in therapeutic uses, pharmacokinetics, and adverse effects profiles [ ]. Compared with…

Plasma products

General information Plasma products are used to substitute plasma proteins and in plasma exchange. Fresh frozen plasma is used as a source of coagulation factors in deficiency, if no purified factors are available. Intensive plasma exchange has been studied in…

Plantaginaceae

General information The family of Plantaginaceae contains two genera: 1. Littorella (littorella) 2. Plantago (plantain) You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…

Plague vaccine

General information Plague vaccine is a suspension of the formaldehyde-killed encapsulated form of Yersinia pestis . Primary immunization involves three doses given intramuscularly. The Working Group on Civilian Biodefense has developed consensus-based recommendations for measures to be taken by medical…

Pizotifen

See also Antihistamines General information Pizotifen is a 5HT receptor antagonist chemically related to the tricyclic antidepressants, with a five-membered third ring containing a sulfur atom. It has been suggested that adverse reactions to pizotifen resemble those of amitriptyline […

Pirprofen

See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Pirprofen is a non-steroidal anti-inflammatory drug, a phenylpropionic acid derivative. It has been used to treat rheumatoid arthritis [ ], osteoarthritis [ ], and ankylosing spondylitis [ , ], and as an…