See also Anesthetics, local General information Bupivacaine is a long-acting aminoamide local anesthetic with significantly more systemic toxicity than lidocaine. In a randomized controlled study after total knee arthroplasty in 14 patients the effects of a continuous infusion of intra-articular…
See also Diuretics General information Bumetanide is very similar in most respects to furosemide, although it is more potent mole for mole. An oral dose of 1–4 mg often suffices for ordinary use compared with 40–160 mg of furosemide. Most…
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General information Buflomedil hydrochloride is a vasoactive drug with a variety of actions. It is an alpha-adrenoceptor antagonist and a weak calcium channel blocker. It inhibits platelet aggregation and improves erythrocyte deformability. However, its mechanism of action in peripheral vascular…
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General information Bucillamine (mercaptomethylpropanoylcysteine) is chemically related to penicillamine and is also used in rheumatoid arthritis. Most of the information on bucillamine comes from Japan, its country of origin [ ]. The patterns of adverse reactions to sulfhydryl compounds that…
General information Bryostatins are naturally occurring antineoplastic macrocyclic lactones derived from the marine invertebrate Bugula neritina , different varieties being isolated from different populations of the same species. More than 13 structurally related compounds have been isolated [ , ],…
See also Benzodiazepines General information Brotizolam is a triazolothienodiazepine used in the treatment of insomnia and also has anticonvulsant, antianxiety and muscle relaxant properties. It reduces latency to sleep, reduces the number of awakenings and waking time during sleep, and…