Category Internal Medicine

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See also Antihistamines General information Brompheniramine is a first-generation antihistamine, an alkylamine derivative, with antimuscarinic and moderate sedative actions. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

General information Bromocriptine is an ergot derivative. High doses (for example 30–75 mg/day orally) are used in Parkinson’s disease; low doses (2.5–5.0 mg/day) are used for prostatic tumors and to suppress lactation. The adverse reactions are dose-dependent and, so far…

General information Bromhexine is taken orally or by aerosol and reduces sputum viscosity as measured ex vivo. Although it is still used empirically by some physicians, there have been no controlled studies showing a significant improvement in clinical status or…

See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information Bromfenac sodium (2-amino-3-(4-bromo-benzoyl)-benzeneacetic acid sodium salt sesquihydrate) has a safety profile apparently similar to that of other NSAIDs [ ]. It was approved by the FDA in 1997 for short-term management of…

See also Benzodiazepines General information Bromazepam, a moderately short-acting benzodiazepine (half-life about 12 hours), has been used in the treatment of anxiety states and has the usual effects of benzodiazepines, for example amnesia and depressed psychomotor performance, although it causes…

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General information Brimonidine is a highly selective potent α 2 -adrenoceptor agonist, which is distinguished from clonidine by a chemical modification that reduces its ability to cross the blood–brain barrier. Like apraclonidine, brimonidine has been used to treat glaucoma. However,…

General information Bretylium, originally introduced as a hypotensive agent but no longer used as such, has not been extensively used as an antidysrhythmic drug. Its clinical pharmacology, uses, efficacy, and adverse effects have been reviewed [ ]. Adverse reactions have…

General information Brequinar (DUP 785, NSC 368390) is a quinoline carboxylic acid derivative that inhibits pyrimidine synthesis by inhibiting dihydro-orotate dehydrogenase. It was originally developed as an anticancer drug, but has also been investigated for its immunosuppressant activity after transplantation.…