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Acquired Cutaneous Paraneoplastic Syndromes Description ■ Some cutaneous signs are specific enough to warrant a search for occult malignancy. ■ Acquired cutaneous paraneoplastic syndromes involve cutaneous findings associated with or related to internal malignancy. ■ This chapter will discuss pruritus,…

Erythema Toxicum Neonatorum Description ■ Erythema toxicum neonatorum is a common benign transient pustular eruption seen in the newborn period. History ■ Erythema toxicum neonatorum occurs more commonly in healthy term infants than in premature and low birth weight infants.…

Androgenic Alopecia (Male Pattern Baldness) Description ■ Androgenic alopecia is premature loss of hair of the central scalp. History ■ Alopecia is a physiologic reaction induced by androgens in genetically predisposed men. ■ The pattern of inheritance is probably polygenic.…

Infantile Hemangiomas Description ■ Infantile hemangiomas are benign red, purple, or blue vascular neoplasms occurring within the first year of life; they consist of proliferating endothelial-like cells. ■ Terms such as strawberry hemangioma and cavernous hemangioma should be discarded because…

Acquired Melanocytic Nevi (Moles) Description ■ Acquired melanocytic nevi are common benign skin tumors composed of melanocyte-derived nevus cells. History ■ Acquired melanocytic nevi are more common in whites than Asians and Africans. ■ Numbers of acquired melanocytic nevi peak…

Basal Cell Carcinoma Description ■ Basal cell carcinoma is a skin cancer derived from the basal layer of keratinocytes of the epidermis. ■ It is the most common cutaneous malignancy and most common cancer in humans. ■ If left untreated,…

Seborrheic Keratosis Description ■ A seborrheic keratosis is a common, benign, persistent epidermal lesion with variable clinical appearance. ■ It is one of the most common benign growths seen on the skin. ■ These keratoses have multiple clinical variations and…

Sun-Damaged Skin, Actinic-Damaged Skin, and Photoaging Description ■ Sun-damaged skin is easily recognizable and shows specific skin findings, resulting from damage due to ultraviolet radiation (UVR). History ■ Acute exposure to UVR results in sunburn and is especially caused by…

Lupus Erythematosus General Description ■ Cutaneous lupus erythematosus is a disease with a wide spectrum of manifestations ranging from solitary chronic skin lesions in chronic cutaneous lupus erythematosus (CCLE), to widespread polymorphous lesions in subacute cutaneous lupus erythematosus (SCLE), to…

Dermatitis Herpetiformis Description ■ Dermatitis herpetiformis (DH) is a chronic pruritic vesicular rash commonly occurring on the extensor surfaces and is a manifestation of gluten sensitivity. History ■ In adults, DH is twice as common in males. ■ In children,…