Category Dermatology

Eczema

Acute Eczematous Inflammation Description ■ Acute eczematous inflammation is characterized clinically by erythema, edema, and vesiculation. Weeping or oozing of acute lesions is typical. Pruritus is often severe. History ■ There are multiple causes of acute eczema. They include allergic…

Topical Therapy

Basic Principles of Treatment Maintaining the Skin Barrier ■ The skin assists in fluid homeostasis and protects against infections, toxins, and harmful effects of ultraviolet radiation. ■ The outermost layer of the epidermis, the stratum corneum, provides this protection through…

Mechanism of Action of Sclerotherapy

General Mechanism for Producing Endothelial Damage Sclerotherapy refers to the introduction of a foreign substance into the lumen of a vessel, aiming to create venous wall damage leading to occlusion of the vessel ( Fig. 7.1 ). This procedure, when…

Use of Compression Therapy

Historical Development The oldest known illustration of compression bandages dates back to the Neolithic Age (5000–2500 bc ) ( Fig. 6.1 ). The ancient Hebrews, Egyptians, Greeks and Romans used compression therapy for treatment of wounds and ulcers, as described…

Pathophysiology of Telangiectasias

The term telangiectasia was coined in 1807 by Von Graf to describe a superficial vessel of the skin visible to the human eye. These vessels measure 0.1–1 mm in diameter and represent an expanded venule, capillary or arteriole. Telangiectasias that originate…

Pathophysiology of Varicose Veins

Essentially, three components of the venous system of the leg act in concert: deep veins, superficial veins and perforating-communicating veins. Dysfunction in any of these three systems results in dysfunction of the other two ( Fig. 3.1 ). When the…