Lumps and bumps A wide variety of conditions affecting the skin and subcutaneous tissues present as papulonodular lesions, or ‘lumps and bumps.’ Benign and malignant neoplasms, hamartomas, and inflammatory and infectious disorders, as well as a number of infiltrative diseases,…
Acneiform disorders Neonatal acne (neonatal cephalic pustulosis) Neonatal acne (acne neonatorum) is a very common newborn eruption, occurring in up to 20% of healthy babies. Lesions are not present at birth but typically appear within the first 2–3 weeks of…
Introduction Hyperpigmented lesions, presenting at birth and during the first few weeks of life, are quite common. Pigmented lesions can range from small and isolated to large and multiple. They can exist independently, or in association with other signs and…
Introduction A diverse group of conditions present with hypopigmentation in neonates and infants. A practical clinical approach would be to categorize them according to the distribution of the hypopigmentation: generalized, mosaic, or localized ( Box 23.1 ). Some may be…
Introduction to vascular malformations In 1982, Mulliken and Glowacki proposed a biologic classification of vascular birthmarks that has become widely accepted. It was modified slightly in 1996 by the International Society for the Study of Vascular Anomalies (ISSVA). Two major…
Infantile hemangioma Infantile hemangioma (IH) is the most common vascular tumor encountered during early infancy. It is a benign proliferation of endothelial cells that characteristically undergoes a phase of rapid growth followed by slow spontaneous involution. Although large population-based studies…
Introduction In this chapter, a number of non-related entities will be discussed. They appear grouped by convenience, and represent a heterogeneous group of genetic and acquired diseases with a common ground of an immunologic pathophysiology. Several disorders appear to represent…
Introduction The term ‘inherited disorders of cornification’ covers a wide range of genetic conditions with molecular defects that preclude the formation of a normal epidermis. The term is usually considered to include entities divided on morphological grounds into ichthyoses, follicular…
Erythrodermas The term ‘erythroderma’ is used in dermatology to describe a skin eruption characterized by diffuse erythema, usually in association with scaling. Infantile erythroderma is caused by or associated with a large number of disorders ( Box 18.1 ). The…
Introduction Eruptions in the diaper region have diverse origins. This chapter will review eruptions, both common and uncommon, that have major findings in the diaper area not only in neonates but also in young infants ( Box 17.1 ). Many…