Category Anesthesia

Prader-Willi Syndrome

Risk Prevalence: 1:25,000 Incidence: 1:10,000-15,000 Racial prevalence: None Gender predominance: Similar frequency in both sexes and all races Most common syndromic form of obesity, affects 350,000–400,000 individuals worldwide Annual death rate is 3% versus 1% in the general population, primarily…

Portal Hypertension

Risk Hepatic cirrhosis has a prevalence of about 1–3:1000. At the time of diagnosis of cirrhosis, 50% of pts will already demonstrate sequelae of portal hypertension. Also, in the setting of schistosomiasis (mainly in developing countries), portal vein thrombosis, Budd-Chiari…

Pompe Disease

Risk Combined incidence (infantile vs. late-onset): 1:40,000. Infantile form has higher incidence in African-American and Chinese populations. Late-onset disease has a higher incidence in the Netherlands. Perioperative Risks Respiratory insufficiency Aspiration pneumonia Pulm edema Myocardial ischemia Worry About Respiratory insufficiency,…

Polymyositis

Risk Annual incidence in USA: 5.5:1,000,000, most prevalent among black women Annual incidence around the world: 1.9-7.7:1,000,000, although comprehensive epidemiologic data are lacking Perioperative Risks Delayed recovery from muscle relaxation Aspiration pneumonitis Cardiac arrhythmias CHF Worry About Increased risk of…

Polycythemia Vera

Risk Prevalence: 22:100,000; twice as high among men as women. Higher prevalence in Jewish people of European origin. Prevalence increases with advancing age (rare in those <30 y). Perioperative Risks Risk of deep venous thrombosis, pulmonary emboli Risk of coronary,…

Poliomyelitis

Risk Acute disease eradicated in USA and most of Europe owing to effective vaccination (last USA case reported in 1979 and last case in the western hemisphere in Peru in 1991). Small parts of Africa and Asia still have areas…

Pneumonia, Ventilator-Associated

Risk Incidence of VAP is 1.2–8.5:1000 ventilator days; occurs in 9–27% of intubated mechanically ventilated pts Risk greatest in the first 5 d of mechanical ventilation Increased risk: Male sex; admission for trauma; underlying disease severity; surgery; previous antibiotic exposure…