Category Anesthesia

The Premature Infant

In the last several decades, the incidence of prematurity in the United States has risen to 11.5%. Maternal risk factors for prematurity include absence of prenatal care, low socioeconomic status, tobacco abuse, poor nutrition and genitourinary tract infections, to name…

Endocrine Diseases

Diabetes Mellitus The endocrine condition most frequently encountered in the perioperative period in children is diabetes mellitus. Diabetes mellitus is the result of an absolute or functional deficiency of insulin production by the pancreas. In type 1 diabetes, this deficiency…

Oncologic Diseases

Common Oncologic Disorders Leukemia The leukemias, which result from malignant transformation of early hematopoietic stem cells, are some of the most common malignancies of childhood ( Table 8.1 ). Acute lymphoblastic leukemia (ALL) accounts for 75% of all childhood acute…

Hematologic Diseases

Inherited Coagulation Disorders Hemophilia The hemophilias are a group of X-linked recessive bleeding disorders characterized by insufficient production of coagulation factor VIII (hemophilia A) or factor IX (hemophilia B). Formation of the platelet plug (primary hemostasis) is normal; however, stabilization…