Category Internal Medicine

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General information Dexibuprofen is the dextrorotatory isomer of ibuprofen. Clinical experience is still inadequate to judge its safety profile, although there are claims that it is of comparable safety to celecoxib [ ]. Pharmacokinetics The pharmacokinetics of dexibuprofen 400 mg…

See also Antihistamines General information Dexchlorpheniramine maleate [ ] is the dextrorotatory isomer of chlorphenamine. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…

See also Antihistamines General information Dexbrompheniramine is the dextrorotatory isomer of the first-generation H 1 antihistamine brompheniramine. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

See also Amphetamines General information Dexamfetamine or (+)-amfetamine is significantly more potent than (−)-amfetamine. The use of dexamfetamine as an appetite suppressant has rapidly declined, because of appreciation of its potential for abuse and addiction. These arise mainly from euphoria,…

See also Vasopressin and analogues General information Desmopressin ( N -deamino-8- d -arginine vasopressin, dDAVP) is a longer acting analogue of vasopressin. It has very little vasoactive effect but is antidiuretic by an action on vasopressin V 2 receptors in…

See also Antihistamines General information Desloratadine is the primary metabolite of loratadine, with superior H1 receptor binding, potent antihistaminic activity compared with the parent compound, and proven efficacy in allergic disease [ ]. It is effective and well tolerated in…

See also Anesthetics, general General information Desflurane is identical in structure to isoflurane, except that it is halogenated completely with fluorine instead of fluorine and chlorine. Desflurane is a volatile anesthetic that combines low blood gas solubility with moderate potency…

General information Deoxyspergualin is a synthetic analogue of the immunosuppressive anti-tumor antibiotic spergualin. It contains the polyamine spermidine as part of its structure and has similar properties and mechanisms of action to ciclosporin and the calcineurin inhibitors. It has been…

General information Denileukin diftitox is a genetically engineered fusion protein combining the enzymatically active domains of diphtheria toxin and the full-length sequence for interleukin-2 (IL-2). It targets lymphoma cells that express the high-affinity IL-2 receptor. In vitro, the retinoid X…