See also Cytotoxic and immunosuppressant drugs General information Cytarabine is a pyrimidine nucleoside that is used to treat acute myelogenous leukemia and lymphocytic leukemias. It is activated intracellularly by deoxycytidine kinase to phosphorylated nucleotides that interfere with DNA synthesis in…
See also Antihistamines General information Cyproheptadine is a first-generation antihistamine with antiserotoninergic effects [ ]. It has been used because of its appetite-stimulating capacity. Drowsiness and other adverse effects common to the first-generation antihistamines are common. Organs and systems Nervous…
See also Antituberculosis drugs General information Cycloserine is an aminoisoxazolidone that shows no cross-resistance with other tuberculostatic agents [ ]. Because of its high toxicity, it should only be used when micro-organisms are resistant to other drugs (relapse or primary…
See also Anesthetics, general General information Cyclopropane is an inhalational anesthetic gas. Its minimum alveolar concentration (MAC) is 9.2%. Because of the risk of explosion, it is usually administered by closed circuit [ ]. Organs and systems You’re Reading a…
General information Cyclophosphamide is an alkylating nitrogen mustard derivative mainly used in oncology patients [ ] or in conditioning regimens for bone marrow transplantation. Its immunosuppressant properties have been used in organ transplantation and more often in chronic inflammatory disorders…
See also Anticholinergic drugs General information Cyclopentolate is an anticholinergic drug used in eye-drops as a mydriatic. It can cause both local [ ] and systemic adverse reactions [ , ]. Organs and systems Nervous system Seizures have occasionally been…
General information Cyclofenil is a weak non-steroidal compound related to diethylstilbestrol. It has two different actions on the hypothalamic–hypophyseal axis, an estrogen-like action that reduces serum FSH concentrations and an antiestrogen-like action that reduces serum prolactin concentrations [ ]. It…
General information Cyclobenzaprine is a centrally acting skeletal-muscle relaxant, claimed to be effective in providing relief of muscle spasm, pain and tenderness, and in reducing the limitations imposed thereby on normal daily activities. The recommended total oral daily dose is…
See also : Antihistamines General information Cyclizine is a first-generation antihistamine, a piperazine derivative, with sedative and antimuscarinic activity, although its sedative effects are not marked. Organs and systems You’re Reading a Preview Become a Clinical Tree membership for Full…
General information Cyclazocine is an agonist at KOR(OP 2 , κ) opioid receptors and it is its affinity for these receptors that is thought to account for disruption of the normal sleep pattern, urination, and sustained arousal that it causes…