See also Non-steroidal anti-inflammatory drugs (NSAIDs) General information In a short-term multicenter study of flurbiprofen only 6% of patients were withdrawn because of adverse reactions [ ]. However, in a prolonged open study in 1200 patients, more than 50% reported…
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General information Flupirtine is a non-opiate, centrally acting analgesic, with muscle relaxant properties. It causes predominantly nervous system adverse reactions (visual, disorientation, confusion, tremor). About 26% of patients develop minor adverse reactions [ ]. Drug studies You’re Reading a Preview…
See also Neuroleptic drugs General information Fluphenazine is a phenothiazine neuroleptic drug. In a double-blind comparison of a group of stabilized outpatients taking a low dosage of fluphenazine enanthate (1.25–5 mg every 2 weeks) with a group taking a standard…
See also Neuroleptic drugs General information Flupentixol is a thioxanthene neuroleptic drug. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
See also Selective serotonin re-uptake inhibitors (SSRIs) General Information Fluoxetine is a selective serotonin re-uptake inhibitor (SSRI). The manufacturers of fluoxetine have published a review of the adverse effects and reactions that were noted in 1378 patients who took it…
See also Cytotoxic and immunosuppressant drugs General information Fluorouracil is a fluorinated pyrimidine, which is converted intracellularly to the active form, fluorodeoxyuridine monophosphate, which inhibits thymidylate synthetase and hence reduces the production of thymidylic acid, the deoxyribonucleotide of thymine (5-methyluracil),…
General information Following the introduction of the first quinolone antibiotic (nalidixic acid, see separate monograph), structural modifications to the basic quinolone and naphthyridone nucleus and to the side-chains produced fluoroquinolones with improved coverage of bacterial pathogens, with high activity against…
General information Fluoride is the single most potent bone-forming agent currently available for therapeutic use [ ]. The active moiety is the fluoride ion itself, and its main pharmacological effect is on dental enamel and bone. Fluoride ions bind to…
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